Comparable rates of gene loss and functional divergence after genome duplications early in vertebrate evolution.

Explore this paper's citation graph

Summary

Gene families resulting from genome duplications in humans and mice and the frequency distribution of gene family size showed that duplicated genes are almost as likely to acquire a new and essential function as to be lost through acquisition of mutations that compromise protein function.

Type
article
Published
1997-11-01
Cited by
237
References
39
Access
Open access

Keywords

Gene duplication, Biology, Functional divergence, Gene, Genome

References

Cited by

Related papers