Superfamily of steroid nuclear receptors: positive and negative regulators of gene expression
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Summary
The similarity between all these hormone response enhancer elements, as well as between the receptors themselves, indicates a conserved general strategy for the hormonal control of transcription by steroids.
- Type
- review
- Published
- 1991-06-01
- Cited by
- 283
- References
- 57
- OpenAlex
- https://openalex.org/W1595544422
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1464261
Keywords
Nuclear receptor, Enhancer, PELP-1, Transcription factor, Promoter
References
- Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors.
- Too many transcription factors: positive and negative interactions.
- Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse
- Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.
- The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates.
- Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor
- Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing
- The human estrogen receptor has two independent nonacidic transcriptional activation functions.
- Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps
- Murine isoforms of retinoic acid receptor gamma with specific patterns of expression.
- Puffs, genes, and hormones revisited.
- Retinoic acid causes an anteroposterior transformation in the developing central nervous system
- Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis.
- Steroid hormone receptors compete for factors that mediate their enhancer function.
- Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor.
- The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.
- Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.
- The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements.
- Nuclear receptors enhance our understanding of transcription regulation.
- Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.
Cited by
- Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone.
- The Androgen Receptor: Structure, Mutations, and Antiandrogens
- Structure and regulation of the amiloride-sensitive epithelial sodium channel.
- The cell surface receptor encoded by the proto-oncogene KIT and its ligand.
- Thymocyte apoptosis by glucocorticoids and cAMP.
- Progesterone receptors in the human placenta: Expression, signalling characteristics and functional relevance
- Vitamin D and Prostate Cancer: Biologic Interactions and Clinical Potentials
- Isolation and cloning of human peroxisome proliferator activated receptor gamma cDNA.
- Alveolar fluid clearance in developing lungs and its role in neonatal transition.
- Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling
- Androgen receptor mutations in prostate cancer.
- Signalling Mechanisms — from Transcription Factors to Oxidative Stress
- Regulation of endometrial regeneration; mechanisms contributing to repair and restoration of tissue integrity following menses
- Molecular basis for abnormal parturition in zinc deficiency in rats.
- Inducible protein expression using a glucocorticoid-sensitive vector.
- Growth inhibitory effects of 1alpha, 25-dihydroxyvitamin D(3) are mediated by increased levels of p21 in the prostatic carcinoma cell line ALVA-31.
- Transforming growth factor beta 1 functions in monocytic differentiation of hematopoietic cells through autocrine and paracrine mechanisms.
- Clinical Use of PPARγ Ligands in Cancer
- Modulation of androgen receptor transcriptional activity by the estrogen receptor.
- Sexual dimorphism in the vertebrate nervous system
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