Naïve T cell maintenance and function in human aging

Keywords

Biology, Repertoire, Naive T cell, Population, T cell

References

• Telomere-based therapy for immunosenescence.Beatriz Hernández Cembellín — 2002
• Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with ageCarlos Barros Guimeráns — 2012
• The role of inflammation in age-related diseaseT. Kevin Howcroft, Judith Campisi, Germaine M. Buck Louis — 2013
• Human cytomegalovirus‐specific CD8+ T‐cell expansions contain long‐lived cells that retain functional capacity in both young and elderly subjectsDiana L. Wallace, Joanne E. Masters, Catherine M. de Lara — 2011
• Response to Comment on “Homeostasis of the Naive CD4+ T Cell Compartment during Aging”Ryan D. Kilpatrick, Tammy M. Rickabaugh, Beth D. Jamieson — 2008
• Telomere dysfunction, autoimmunity and aging.Philipp J. Hohensinner, Jörg J. Goronzy, Cornelia M. Weyand — 2011
• The Influence of Age on T Cell Generation and TCR Diversity1Keith Naylor, Guangjin Li, Abbe N. Vallejo — 2005
• Direct Measurement of T Cell Subset Kinetics In Vivo in Elderly Men and Women1Diana L. Wallace, Yan Zhang, Hala Ghattas — 2004
• Distinct Mechanisms Control Human Naive and Antigen-Experienced CD8+ T Lymphocyte Proliferation1Marco Migliaccio, Pedro Miguel Sousa Alves, Pedro Romero — 2006
• The Many Faces of IL-7: From Lymphopoiesis to Peripheral T Cell MaintenanceTerry J. Fry, Crystal L. Mackall — 2005
• Two separate defects, affecting true naïve (TNa) or virtual memory (VM) T cell precursors, combine to reduce naïve T cell responses with agingKristin R. Renkema, Gang Li, Angela Wu — 2013
• Aging of the T cell compartment in mice and humans: from no naïve expectations to foggy memoriesJanko Nikolich‐Žugich — 2014
• Homeostasis of naive and memory T cells.Charles D. Surh, Jonathan Sprent — 2008
• Quantifying T Lymphocyte TurnoverRob J. de Boer, Alan S. Perelson — 2013
• Diversity and clonal selection in the human T-cell repertoireQian Qi, Yi Liu, Yong Cheng — 2014
• Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditionsYun Lin, Amanda K. Damjanovic, E. Jeffrey Metter — 2015
• B cell maintenance and function in aging.Igor Kogut, Jean L. Scholz, Michael P. Cancro — 2012
• Autophagy is essential for effector CD8 T cell survival and memory formationXiaojin Xu, Koichi Araki, Shuzhao Li — 2014
• p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.Sian M. Henson, Alessio Lanna, Natalie E. Riddell — 2014
• Chronic inflammation and aging: DNA damage tips the balanceMary Cavanagh, Cornelia M. Weyand, Jörg J. Goronzy — 2012

Cited by

• Transcriptomic profiles of aging in naïve and memory CD4+ cells from miceEphraim Chirwa, V. Mhoni, R. Kachule — 2017
• Emerging concepts in tissue-resident T cells: lessons from humansJoseph J.C. Thome, Donna L. Färber — 2015
• Age-associated Failure to Adjust Type I Interferon Receptor Signaling Thresholds after T-cell ActivationGuangjin Li, Jihang Ju, Cornelia M. Weyand — 2015
• High-throughput sequencing insights into T-cell receptor repertoire diversity in agingJörg J. Goronzy, Qian Qi, Richard A. Olshen — 2015
• Thyroid hormones and their membrane receptors as therapeutic targets for T cell lymphomas.Graciela Cremaschi, Florencia Cayrol, Helena Sterle — 2016
• Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.Theo van den Broek, Eveline M. Delemarre, Willemijn J.M. Janssen — 2016
• Is immunosenescence influenced by our lifetime “dose” of exercise?James Turner — 2016
• Expression of death receptor 3 on peripheral blood mononuclear cells differes in adult IBD patients and children with newly diagnosed IBDTomasz Ślebioda, Agnieszka Bojarska−Junak, Marta Cyman — 2017
• Restoration of Thymus Function with Bioengineered Thymus OrganoidsAsako Tajima, Isha Pradhan, Massimo Trucco — 2016
• Medullary thymic epithelial stem cells: role in thymic epithelial cell maintenance and thymic involutionYoko Hamazaki, Miho Sekai, Nagahiro Minato — 2016
• Virus-host interactions of emerging respiratory pathogensJanne Tynell — 2016
• Molecular tuning of telomerase activity in senescent human T cellsA. Lanna — 2016
• The Ageing Immune System and HealthV. Bueno, J. Lord, Thomas A. Jackson — 2017
• Construction of Thymus Organoids from Decellularized Thymus ScaffoldsAsako Tajima, Isha Pradhan, Xuehui Geng — 2016
• Age-associated changes in human hematopoietic stem cells.Wendy W. Pang, Stanley L. Schrier, Irving L. Weissman — 2017
• Lymphocyte generation and population homeostasis throughout lifeRolando E. Yanes, Claire E. Gustafson, Cornelia M. Weyand — 2016
• Partial MHC Class II Constructs as Novel Immunomodulatory Therapy for StrokeGil Benedek, Arthur A. Vandenbark, Nabil J. Alkayed — 2016
• Longterm maintenance of human naive T cells through in situ homeostasis in lymphoid tissue sitesJoseph J.C. Thome, Boris Grinshpun, Brahma V. Kumar — 2016
• Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged miceSi‐Young Cho, Juewon Kim, Ji Hae Lee — 2016
• Aging of the Immune System. Mechanisms and Therapeutic Targets.Cornelia M. Weyand, Jörg J. Goronzy — 2016

Related papers

• Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling1Huaizhong Hu, Yinchen Dong, Ping Feng — 2003
• Reconstitution of CMV pp65 and IE-1-specific IFN-γ CD8+ and CD4+ T-cell responses affording protection from CMV DNAemia following allogeneic hematopoietic SCTNuria Tormo, Carlos Solano, Isabel Benet — 2011
• Clinical significance and expression of T cell subsets in peripheral blood from patients with ankylosing spondylitisXiuzhen Zhao, Haicheng Song, Liufu Cui — 2009
• Generation of class I MHC-restricted T-T hybridomas.Kenneth L. Rock, Lisa Rothstein, S Gamble — 1990
• Effect of Shengyu decoction on changing T cell subgroups and cytokine levels in cyclophamide-induced miceGang Cheng — 2009
• GSK-3β inhibition preserves naive T cell phenotype in bone marrow reconstituted mice.Sylvie Shen, Guy Klamer, Ning Xu — 2013
• Prolonged costimulation is required for naive T cell activation.Robert Liwski, Jennifer C. Chase, William H. Baldridge — 2006
• Intracellular Analysis of Interleukin-2 Induction Provides Direct Evidence at the Single Cell Level of Differential Coactivation Requirements for CD45RA+ and CD45RO+ T Cell SubsetsDarren G. Woodside, Dorothy A. Long, Bradley W. McIntyre — 1999