Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.
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Summary
Serine/threonine phosphorylation of IRS 1 induced by okadaic acid reduces the ability of the insulin receptor to phosphorylate IRS 1 and to dock one of its interacting molecules, i.e. PI 3-kinase.
- Type
- article
- Published
- 1994-02-25
- Cited by
- 291
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1570362997
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22246598
Keywords
Insulin receptor, Okadaic acid, Phosphorylation, Tyrosine phosphorylation, Insulin receptor substrate
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