Brain-derived neurotrophic factor.
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Summary
Since the purification of BDNF in 1982, a great deal of evidence has mounted for its central roles in brain development, physiology, and pathology, and application of the trophic properties ofBDNF may lead to novel therapeutic options in neurodegenerative diseases and perhaps even in neuropsychiatric disorders.
- Type
- review
- Published
- 2004-09-01
- Cited by
- 1,851
- References
- 169
- Access
- Open access
- OpenAlex
- https://openalex.org/W1555679702
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1855776
Keywords
Neuroscience, Neocortex, Synaptic plasticity, Neuroplasticity, Hippocampus
References
- GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor.
- Neurotrophins: to cleave or not to cleave.
- Seizures and the regulation of neurotrophic factor and neuropeptide gene expression in brain.
- Anterograde transport of brain-derived neurotrophic factor and its role in the brain
- Neurotrophin-3 Sorts to the Constitutive Secretory Pathway of Hippocampal Neurons and Is Diverted to the Regulated Secretory Pathway by Coexpression with Brain-Derived Neurotrophic Factor
- Purification of a new neurotrophic factor from mammalian brain.
- Regulation of brain-derived neurotrophic factor mRNA levels in hippocampus by neuronal activity.
- Actions of Brain-Derived Neurotrophic Factor in Slices from Rats with Spontaneous Seizures and Mossy Fiber Sprouting in the Dentate Gyrus
- Rapid and selective induction of BDNF expression in the hippocampus during contextual learning
- Brain-Derived Neurotrophic Factor Modulates Nociceptive Sensory Inputs and NMDA-Evoked Responses in the Rat Spinal Cord
- Inhibition of GABAA Synaptic Responses by Brain-Derived Neurotrophic Factor (BDNF) in Rat Hippocampus
- Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
- Neurotrophin-evoked rapid excitation through TrkB receptors
- Infusion of Brain-Derived Neurotrophic Factor into the Lateral Ventricle of the Adult Rat Leads to New Neurons in the Parenchyma of the Striatum, Septum, Thalamus, and Hypothalamus
- Differential Sorting of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal Neurons
- Differential Effects of Protein Synthesis Inhibition on the Activity-Dependent Expression of BDNF Transcripts: Evidence for Immediate-Early Gene Responses from Specific Promoters
- Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
- Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus
- Upregulation of BDNF mRNA Expression in the Barrel Cortex of Adult Mice after Sensory Stimulation
- Selectivity in neurotrophin signaling: theme and variations.
Cited by
- Autoantibodies and depression: evidence for a causal link?
- Suppression of BDNF‐induced expression of neuropeptide Y (NPY) in cortical cultures by oxygen‐glucose deprivation: A model system to study ischemic mechanisms in the perinatal brain
- In vivo induction of glial cell proliferation and axonal outgrowth and myelination by brain-derived neurotrophic factor.
- High consistency of regional cortical thinning in aging across multiple samples.
- Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat.
- Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population
- Serum brain‐derived neurotrophic factor levels in epilepsy
- Changes in plasma Brain-derived neurotrophic factor (BDNF) levels induced by methylphenidate in children with Attention deficit-hyperactivity disorder (ADHD).
- Psychophysiology of dissociated consciousness.
- Traumatic brain injury and cognition.
- BDNF Val66Met Polymorphism on Functional MRI During n-Back Working Memory Tasks
- Effects of Traumeel (Tr14) on Exercise-Induced Muscle Damage Response in Healthy Subjects: A Double-Blind RCT
- The effect of second-generation antipsychotics on hippocampal volume in first episode of psychosis: longitudinal study
- Neuroprotective action of N-acetyl serotonin in oxidative stress-induced apoptosis through the activation of both TrkB/CREB/BDNF pathway and Akt/Nrf2/Antioxidant enzyme in neuronal cells
- Neurotrophins: Role in Placental Growth and Development.
- Effects of exercise on mature or precursor brain‑derived neurotrophic factor pathways in ovariectomized rats.
- Preconditioned neurons with NaB and nicorandil, a favorable source for stroke cell therapy
- BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo
- Hypothalamic-pituitary-adrenal-axis vs. the sympatho-adrenal medullary system in the acute response to psychological stress
- Der Zyklus Belastung – Adaptation
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