Metaplasticity: a new vista across the field of synaptic plasticity.
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Summary
Metaplasticity may serve several functions including providing a way for synapses to integrate a response across temporally spaced episodes of synaptic activity and keeping synapses within a dynamic functional range, and thus preventing them from entering states of saturated LTP or LTD.
- Type
- review
- Published
- 1997-07-01
- Cited by
- 346
- References
- 123
- OpenAlex
- https://openalex.org/W2011264238
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:33285995
Keywords
Metaplasticity, Neuroscience, Synaptic plasticity, Long-term potentiation, Synaptic fatigue
References
- Low concentrations of N-methyl-D-aspartate inhibit the induction of long-term potentiation in rat hippocampal slices.
- Mechanism for a sliding synaptic modification threshold.
- Modulation of both the early and the late phase of mossy fiber LTP by the activation of beta-adrenergic receptors.
- 10 Regulation of Protein Synthesis by Calcium
- Dopamine modulates the slow Ca(2+)-activated K+ current IAHP via cyclic AMP-dependent protein kinase in hippocampal neurons.
- Protein synthesis inhibitors differentially superinduce c‐fos and c‐jun by three distinct mechanisms: lack of evidence for labile repressors.
- Long-term potentiation : from biophysics to behavior
- The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2.
- Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases
- Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex
- Excitatory effects of ACPD receptor activation in the hippocampus are mediated by direct effects on pyramidal cells and blockade of synaptic inhibition.
- Facilitation of long-term potentiation by prior activation of metabotropic glutamate receptors.
- Expression of EPSP/spike potentiation following low frequency and tetanic stimulation in the CA1 area of the rat hippocampus
- Induction and reversal of long-term potentiation by low- and high- intensity theta pattern stimulation
- Modulation of hippocampal long-term potentiation and long-term depression by corticosteroid receptor activation
- Long-term increases in excitability in the CA1 region of rat hippocampus induced by beta-adrenergic stimulation: possible mediation by cAMP
- Long-term increases in the evoked population spike in the CA1 region of rat hippocampus induced by beta-adrenergic receptor activation
- Modulation by dopamine of population responses and cell membrane properties of hippocampal CA1 neurons in vitro.
- Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit.
- Targeting of mRNAs to subsynaptic microdomains in dendrites.
Cited by
- Regulation of synaptic plasticity in memory and memory decline with aging.
- Synaptic plasticity, metaplasticity and BCM theory.
- Regulation of postsynaptic AMPA receptor trafficking by MAPK pathways in Caenorhabditis elegans neurons
- Brain organization and psychodynamics.
- Investigations of neuronal network responses to electrical stimulation in murine spinal cultures.
- Modulation cholinergique à long terme des potentiels évoqués visuels dans le cortex visuel chez le rat
- Metaplastic Regulation of Long-Term Potentiation/Long-Term Depression Threshold by Activity-Dependent Changes of NR2A/NR2B Ratio
- Cellular mechanisms of synaptic plasticity in hippocampal area CA1
- The dopamine system and the pathophysiology of schizophrenia: a basic science perspective.
- Learning, self-organisation and homeostasis in spiking neuron networks using spike-timing dependent plasticity
- Synaptic plasticity: taming the beast
- Hippocampal long‐term depression in freely behaving mice requires the activation of beta‐adrenergic receptors
- Hippocampal long‐term depression is enhanced, depotentiation is inhibited and long‐term potentiation is unaffected by the application of a selective c‐Jun N‐terminal kinase inhibitor to freely behaving rats
- Plastic processes in the dentate gyrus: a computational perspective.
- Primary motor cortical metaplasticity induced by priming over the supplementary motor area
- Priming Stimulation Enhances the Depressant Effect of Low-Frequency Repetitive Transcranial Magnetic Stimulation
- The role of Polo-like kinase 2 in synaptic function and plasticity
- Isometric contraction interferes with transcranial direct current stimulation (tDCS) induced plasticity – evidence of state-dependent neuromodulation in human motor cortex
- Bidirectional long‐term motor cortical plasticity and metaplasticity induced by quadripulse transcranial magnetic stimulation
- Modulation of LTP induction by NMDA receptor activation and nitric oxide release.
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