Familial Danish Dementia: A Novel Form of Cerebral Amyloidosis Associated with Deposition of Both Amyloid‐Dan and Amyloid‐Beta
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Summary
It is shown that ADan is widely distributed in the central nervous system (CNS) in the leptomeninges, blood vessels, and parenchyma and supports the notion that parenchymal amyloid fibril formation is not a prerequisite for the development of neurofibrillary tangles.
- Type
- article
- Published
- 2002-03-01
- Cited by
- 122
- References
- 53
- Access
- Open access
- OpenAlex
- https://openalex.org/W1528717145
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14244284
Keywords
Pathology, Amyloidosis, Cerebral amyloid angiopathy, Parenchyma, Amyloid (mycology)
References
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- Cortical angiopathy in Alzheimer's disease: The formation of dystrophic perivascular neurites is related to the exudation of amyloid fibrils from the pathological vessels
- Neurofilament Monoclonal Antibodies RT97 and 8D8 Recognize Different Modified Epitopes in Paired Helical Filament‐τ in Alzheimer's Disease
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- Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease.
- New Phosphorylation Sites Identified in Hyperphosphorylated Tau (Paired Helical Filament‐Tau) from Alzheimer's Disease Brain Using Nanoelectrospray Mass Spectrometry
- Cytoskeletal pathology in familial cerebral amyloid angiopathy (British type) with non-neuritic amyloid plaque formation
- A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
- The Consortium to Establish a Registry for Alzheimer's Disease (CERAD).
- Functional and structural properties of lipid-associated apolipoprotein J (clusterin).
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- Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.
Cited by
- Aβ species, including IsoAsp23 Aβ, in Iowa-type familial cerebral amyloid angiopathy
- Cerebral Amyloid Angiopathies: A Pathologic, Biochemical, and Genetic View
- CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER’S DISEASE
- Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits.
- Oligomerization and neurotoxicity of the amyloid ADan peptide implicated in familial Danish dementia
- Amyloid diseases at old age : a pathological, epidemiological, and genetic study
- Role of BRI2 in Dementia
- Lessons from a Rare Familial Dementia: Amyloid and Beyond
- Increased AβPP Processing in Familial Danish Dementia Patients
- Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy
- Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: Effects on learning and memory
- Pathogenesis of cerebral amyloid angiopathy.
- Novel Isolated Cerebral AL&lgr; Amyloid Angiopathy With Widespread Subcortical Distribution and Leukoencephalopathy Due to Atypical Monoclonal Plasma Cell Proliferation, and Terminal Systemic Gammopathy
- Massive accumulation of 11C-Pittsburg compound B in the occipital lobes of a patient with early-onset dementia accompanied by muscle weakness and hypertonicity
- Kinetic partitioning between aggregation and vesicle permeabilization by modified ADan.
- Expression of mBRI2 in mice.
- Physicochemical characteristics of soluble oligomeric Aβ and their pathologic role in Alzheimer's disease
- Animal models of human amyloidoses: Are transgenic mice worth the time and trouble?
- Amyloidosis and Alzheimer's disease.
- Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease
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