Growth Hormone Releasing Hormone (GHRH) and the GHRH Receptor
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Summary
The structure, distribution, and function of GHRH and its receptor are discussed, and data about animal and human mutations that help to delineate the role of G HRH and GHRh receptors (GHRH-R) in human disease are presented.
- Type
- review
- Published
- 2002-12-01
- Cited by
- 79
- References
- 96
- OpenAlex
- https://openalex.org/W1514884232
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6263928
Keywords
Computer science
References
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- Regulation of the pituitary somatotroph cell by GHRH and its receptor.
- Growth disorders caused by genetic defects in the growth hormone pathway.
- Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH‐releasing factor neurons.
- Regulational Effect of Ghrelin on Growth Hormone Secretion from Perifused Rat Anterior Pituitary Cells
- Structure and function of the growth-hormone-releasing hormone receptor.
- The little (lit) mutation cosegregates with the growth hormone releasing factor receptor on mouse Chromosome 6
- Topographical and ontogenetic study of the neurons producing growth hormone-releasing factor in human hypothalamus.
- Receptor-mediated actions of growth hormone releasing factor on granulosa cell differentiation.
- Expression of the rat growth hormone-releasing hormone gene in placenta is directed by an alternative promoter.
- Mouse growth-hormone-releasing hormone: precursor structure and expression in brain and placenta.
- Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene.
- Differential gene expression of growth hormone (GH)-releasing hormone (GRH) and GRH receptor in various rat tissues.
- RESPONSES TO ANALOGUES OF GROWTH HORMONE‐RELEASING HORMONE IN NORMAL SUBJECTS, AND IN GROWTH‐HORMONE DEFICIENT CHILDREN AND YOUNG ADULTS
- Binding sites for growth hormone releasing factor on rat anterior pituitary cells
- Molecular basis of the little mouse phenotype and Implications for cell type-specific growth
- Sexually dimorphic expression of pituitary growth hormone-releasing factor receptor in the rat.
Cited by
- A hypothesis for a possible synergy between ghrelin and exercise in patients with cachexia: Biochemical and physiological bases.
- ウシ・グレリン受容体遺伝子の塩基多型、分子進化およびその塩基多型と産肉形質との関連性
- Growth hormone-releasing hormone (GHRH) polymorphisms associated with carcass traits of meat in Korean cattle
- Acromegalia y enfermedad cardiovascular
- Diseases associated with growth hormone-releasing hormone receptor (GHRHR) mutations.
- Identification and functional analysis of novel human growth hormone–releasing hormone receptor (GHRHR) gene mutations in Japanese subjects with short stature
- PKC and ERK are differentially involved in gonadotropin-releasing hormone-induced growth hormone gene expression in the goldfish pituitary.
- Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI)
- Difference in growth hormone response to growth hormone-releasing hormone (GHRH) testing following GHRH subacute treatment in normal aging and growth hormone-deficient adults: Possible perspectives for therapeutic use of GHRH or its analogs in elderly subjects?
- Effect of nutrient restriction on the somatotropes and substance P-immunoreactive cells in the pituitary of the female ovine fetus.
- Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).
- A novel gross indel in the growth hormone releasing hormone receptor gene of Indian IGHD patients.
- Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells and promote their survival
- Antagonist of GH-releasing hormone receptors alleviates experimental ocular inflammation
- Alteration of the miRNA expression profile in male porcine anterior pituitary cells in response to GHRH and CST and analysis of the potential roles for miRNAs in regulating GH.
- Effects of leptin replacement on hypothalamic-pituitary growth hormone axis function and circulating ghrelin levels in ob/ob mice.
- Age-related changes in gene expression of the growth hormone secretagogue and growth hormone-releasing hormone receptors in Holstein-Friesian cattle.
- Single-nucleotide polymorphisms in the promoter of the growth hormone-releasing hormone receptor gene are associated with growth and reproduction traits in chickens.
- The GH1/IGF-1 axis polymorphisms and their impact on breast cancer development
- A 5′UTR SNP of GHRHR locus is associated with body weight and average daily gain in Chinese cattle
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