A hypothesis for a possible synergy between ghrelin and exercise in patients with cachexia: Biochemical and physiological bases.
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Summary
Progressive resistance training is a potent inducer of the secretion the muscle-restricted IGF-1 (mIGF-1) that enhances protein synthesis, increases lean body mass and eventually leads to the improvement of muscle strength, which may serve to circumvent ghrelin resistance and further reduce muscle wasting, which are commonly associated with cachexia.
- Type
- dissertation
- Published
- 2015-12-01
- Cited by
- 13
- References
- 99
- OpenAlex
- https://openalex.org/W26404870
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39776654
Keywords
Humanities, Art
References
- Supraphysiological doses of GH induce rapid changes in cardiac morphology and function.
- IGF-I/IGFBP system: Metabolism outline and physical exercise
- The anti-inflammatory effect of exercise.
- Exercise training‐induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti‐inflammatory influence of exercise?
- Making muscles "stronger": exercise, nutrition, drugs.
- Regulation of muscle mass by growth hormone and IGF‐I
- Growth Hormone Releasing Hormone (GHRH) and the GHRH Receptor
- Elevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure: Relationships Between Ghrelin and Anabolic/Catabolic Factors
- Mechanisms of Growth Hormone (GH) Action
- Therapeutic potential of anamorelin, a novel, oral ghrelin mimetic, in patients with cancer-related cachexia: a multicenter, randomized, double-blind, crossover, pilot study
- Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss.
- Metabolic Status Regulates Ghrelin Function on Energy Homeostasis
- Heterogeneity of Ghrelin/Growth Hormone Secretagogue Receptors
- Ghrelin for cachexia
- A randomized controlled trial on the effectiveness of strength training on clinical and muscle cellular outcomes in patients with prostate cancer during androgen deprivation therapy: rationale and design
- The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.
- The NPY system in stress, anxiety and depression.
- The IGF-I generation test revisited: a marker of GH sensitivity.
- Myonuclear domains in muscle adaptation and disease
- Effect of ghrelin and anamorelin (ONO-7643), a selective ghrelin receptor agonist, on tumor growth in a lung cancer mouse xenograft model
Cited by
- Ghrelin for the management of cachexia associated with cancer.
- Z-505 hydrochloride, an orally active ghrelin agonist, attenuates the progression of cancer cachexia via anabolic hormones in Colon 26 tumor-bearing mice.
- The impact of exercise training on adipose tissue remodelling in cancer cachexia
- Age modifies the association between serum obestatin, appetite and nutritional status in maintenance hemodialysis patients
- Asprosin: Possible target in connection with ghrelin and cytokine network expression in the post-burn treatment.
- Ghrelin as a Promising Therapeutic Option for Cancer Cachexia
- Effects of Exercise on Muscle Fitness in Dialysis Patients: A Systematic Review and Meta-Analysis
- Z-505, an Oral Ghrelin Receptor Agonist, Attenuates Anorexia After Total Gastrectomy in Rats.
- Oxidative stress in exercise training: the involvement of inflammation and peripheral signals
- Cancer-Mediated Muscle Cachexia: Etiology and Clinical Management
- La ghréline et ses analogues dans le traitement de l’anorexie et de la cachexie cancéreuse
- The effect of anamorelin (ONO-7643) on cachexia in cancer patients: Systematic review and meta-analysis of randomized controlled trials
- Physical Activity, Exerkines, and Their Role in Cancer Cachexia
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