The Connections Between Neural Crest Development and Neuroblastoma
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Summary
This review focuses on the development of the peripheral trunk neural crest, the current understanding of how developmental factors may contribute to NB and on recent advances in the identification of important genetic lesions and signaling pathways involved in NB tumorigenesis and metastasis.
- Type
- review
- Published
- 2011-01-01
- Cited by
- 164
- References
- 282
- Access
- Open access
- OpenAlex
- https://openalex.org/W1512398642
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34357892
Keywords
Neural crest, Biology, Neuroblastoma, Identification (biology), Sympathetic nervous system
References
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- Marked and independent prognostic significance of the CpG island methylator phenotype in neuroblastomas.
- MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
- Persistent expression of BMP-4 in embryonic chick adrenal cortical cells and its role in chromaffin cell development
- Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.
- Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification.
- Neuroblastoma as a Neurobiological Disease
- Caspase activation: revisiting the induced proximity model.
- Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma. United Kingdom Children's Cancer Study Group.
- Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
- Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.
- Inhibition of telomerase limits the growth of human cancer cells
Cited by
- The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio
- MYCN and microRNAs in neuroblastoma
- The Role of Intracellular Calcium for the Development and Treatment of Neuroblastoma
- Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells
- The neural crest: a versatile organ system.
- Identification of a putative transcriptome signature common to neuroblastoma and neural crest cells
- Ganglioneuroblastoma in an adult patient
- Peripheral neuroblastomas in dogs: a case series.
- LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/β-Catenin Signaling
- Significance and Therapeutic Value of miRNAs in Embryonal Neural Tumors
- Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells
- Neuroblastoma: The impact of biology and cooperation leading to personalized treatments
- Derivation of Mesenchymal Stromal Cells from Pluripotent Stem Cells through a Neural Crest Lineage using Small Molecule Compounds with Defined Media
- Knockdown of β-catenin expression inhibits neuroblastoma cell growth in vitro and in vivo.
- Organelle asymmetry for proper fitness, function, and fate
- A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
- Genetically engineered murine models – Contribution to our understanding of the genetics, molecular pathology and therapeutic targeting of neuroblastoma
- Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo
- Beta-Actin Is Required for Proper Mouse Neural Crest Ontogeny
- Downregulation of Axl in non-MYCN amplified neuroblastoma cell lines reduces migration.
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