Cellular and molecular mechanisms in the hypoxic tissue: role of HIF‐1 and ROS

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Summary

New developments in HIF‐mediated O2 sensing mechanisms and their interactions with reactive oxygen species–generating pathways in normal and abnormal physiology are summarized.

Type
review
Published
2013-08-01
Cited by
139
References
62
Access
Open access

Keywords

Reactive oxygen species, Cell biology, Transcription factor, Mediator, Oxidative phosphorylation

References

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