Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells.

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Summary

Southern blot analysis of genomic DNA from several mouse strains revealed that 2B4 belongs to a family of closely related genes and is a member of Ig supergene family, and it shows homology to murine and rat CD48 and human LFA-3.

Type
article
Published
1993-11-15
Cited by
230
References
0

Keywords

Biology, Molecular biology, Gene, Southern blot, Major histocompatibility complex

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