Antioxidant properties of (-)-epicatechin-3-gallate and its inhibition of Cr (VI)-induced DNA damage and Cr (IV)- or TPA-stimulated NF-κB activation
Explore this paper's citation graph
Summary
The present studies provide a mechanistic basis for the reported anticarcinogenic properties of EGCG and related tea products.
- Type
- article
- Published
- 2000-03-01
- Cited by
- 110
- References
- 32
- OpenAlex
- https://openalex.org/W1496277303
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26283500
Keywords
Radical, Chemistry, Spin trapping, Xanthine oxidase, Antioxidant
References
- Characterization of a silencer regulatory element in the human interferon-gamma promoter.
- The transition metal-mediated formation of the hydroxyl free radical during the reduction of molecular oxygen by ferredoxin-ferredoxin:NADP+ oxidoreductase.
- Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea.
- Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants.
- Spin trapping for hydroxyl in water: a kinetic evaluation of two popular traps
- Antitumor promoting activity of (−)‐epigallocatechin gallate, the main constituent of “Tannin” in green tea
- Spin trapping. Kinetics of the reaction of superoxide and hydroxyl radicals with nitrones
- Detection and identification of short-lived free radicals by an electron spin resonance trapping technique
- Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI).
- Polyphenols as inhibitors of carcinogenesis.
- Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical.
- The Role of Free Radicals in Toxicity and Disease
- Spin trapping: ESR parameters of spin adducts.
- Cr(IV) causes activation of nuclear transcription factor-kappa B, DNA strand breaks and dG hydroxylation via free radical reactions.
- On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species.
- Free radicals in toxicology.
- Reduction of chromium(VI) and its relationship to carcinogenesis.
- The nutritional and therapeutic value of tea—a review
- The data support a role for antioxidants in reducing cancer risk.
- Chromate-induced chromium(V) formation in live mice and its control by cellular antioxidants: an L-band electron paramagnetic resonance study.
Cited by
- Potential role of green tea catechins in the management of oxidative stress-associated infertility.
- Microwave-assisted Fenton-like decolorization of methyl orange solution using chromium compounds
- Nutrition for healthy skin : strategies for clinical and cosmetic practice
- Free radical processes in green tea polyphenols (GTP) investigated by electron paramagnetic resonance (EPR) spectroscopy.
- Botanical Antioxidants for Skin Health in the World of Cosmeceuticals
- Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite
- The green tea polyphenol (−)-epigallocatechin-3-gallate inhibits amyloid-β evoked fibril formation and neuronal cell death in vitro
- Effects of EGCG on voltage-gated sodium channels in primary cultures of rat hippocampal CA1 neurons.
- Essiac tea: scavenging of reactive oxygen species and effects on DNA damage.
- Epigallocatechin gallate protects against nitric oxide-induced apoptosis via scavenging ROS and modulating the Bcl-2 family in human dental pulp cells.
- The Antioxidant (–)-Epigallocatechin-3-gallate Inhibits Rat Hepatic Stellate Cell Proliferation in Vitro by Blocking the Tyrosine Phosphorylation and Reducing the Gene Expression of Platelet-derived Growth Factor-β Receptor*
- Inflammatory Process and Molecular Targets for Antiinflammatory Nutraceuticals.
- SIMULTANEOUS DETERMINATION OF CAFFEINE AND CATECHINS IN TEA EXTRACTS BY HPLC
- Antioxidative properties of black tea.
- Antioxidant effects of green tea
- Analysis of free-radical scavenging of Yerba Mate (Ilex paraguriensis) using electron spin resonance and radical-induced DNA damage.
- Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-κB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells
- Green Tea Catechins and L-Theanine in Integrative Cancer Care: A Review of the Research
- Immune cell activation and subsequent epithelial dysfunction by Staphylococcus enterotoxin B is attenuated by the green tea polyphenol (-)-epigallocatechin gallate.
- Glycoprotein Isolated from Solanum nigrum L. Modulates the Apoptotic-Related Signals in 12-O-Tetradecanoylphorbol 13-Acetate-Stimulated MCF-7 Cells
Related papers
- Effects of tenidap on superoxide-generating enzymes. Non-competitive inhibition of xanthine oxidase.
- Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.
- Generation of superoxide from nitric oxide synthase
- Spin-trapping evidence that graded myocardial ischemia alters post-ischemic superoxide production.
- Redox cycling of potential antitumor aziridinyl quinones.
- Synthesis and structure of 5,5-diethoxycarbonyl-1-pyrroline N -oxide (DECPO). Application to superoxide radical trapping
- Detection of superoxide production in stimulated and unstimulated living cells using new cyclic nitrone spin traps.
- Can spin trapping compounds like PBN protect against self-inflicted damage in polymorphonuclear leukocytes?
- ESR-spin trapping in the presence of cyclodextrins. Detection of PBN-superoxide spin adduct
- Quantitative measurement of superoxide generation using the spin trap 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide.