On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus
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Summary
It is shown that all bannedanin‐resistant variants exhibit mutations in helicase and membrane protein, although no evidence of bananin interference on their mutual interaction has been found.
- Type
- article
- Published
- 2010-12-06
- Cited by
- 15
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W1488422853
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32526455
Keywords
Helicase, Mutation, Coronavirus, RNA Helicase A, Severe acute respiratory syndrome coronavirus
References
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- SARS-associated Coronavirus Transmitted from Human to Pig
- Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin
- Mouse Hepatitis Virus Replicase Protein Complexes Are Translocated to Sites of M Protein Accumulation in the ERGIC at Late Times of Infection
- Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.
- Outcome of coronavirus‐associated severe acute respiratory syndrome using a standard treatment protocol
- New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease
- Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease
- SARS virus infection of cats and ferrets
- Electrostatics of nanosystems: Application to microtubules and the ribosome
- A review of studies on animal reservoirs of the SARS coronavirus
- The Adamantane-Derived Bananins Are Potent Inhibitors of the Helicase Activities and Replication of SARS Coronavirus
- A system of protein target sequences for anti-RNA-viral chemotherapy by a vitamin B6-Derived zinc-Chelating trioxa-adamantane-triol
- PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations
- Transcriptional activity of the TFIIA four‐helix bundle in vivo
- Antiviral Activity of 1-Adamantanamine (Amantadine)
- CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
Cited by
- SARS-CoV ORF1b-encoded nonstructural proteins 12–16: Replicative enzymes as antiviral targets
- New quaternary ammonium camphor derivatives and their antiviral activity, genotoxic effects and cytotoxicity
- Increased Antibody Affinity Confers Broad In Vitro Protection against Escape Mutants of Severe Acute Respiratory Syndrome Coronavirus
- An Update on the Bananins: Anti-RNA-Viral Agents with Unique Structural Signature
- A regioselective etherification of pyridoxine via an ortho-pyridinone methide intermediate
- Evaluations Of Severe Acute Respiratory Syndrome Coronavirus Therapeutics And A Viral Capacity For Plasticity And Escape.
- An updated analysis of variations in SARS-CoV-2 genome
- COVID‐19 drug repurposing: Summary statistics on current clinical trials and promising untested candidates
- Evaluation of the potency of FDA-approved drugs on wild type and mutant SARS-CoV-2 helicase (Nsp13)
- Coronaviruses SARS-CoV, MERS-CoV, and SARS-CoV-2 helicase inhibitors: a systematic review of invitro studies
- The Coronavirus helicase in replication
- Targeting NSP-13 protein of SARS CoV-2 with selected natural compounds: An in-silico approach
- Structural elucidation of Langat virus helicase unveils dual-target inhibition for broad-spectrum anti-flaviviruses strategy
- COVID-19 drug repurposing: Summary statistics on current clinical trials and promising untested candidates
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