Genetic predisposition to accelerated decline of lung function in COPD
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Summary
The data to date suggest that products encoded by the alpha-1 antitrypsin, some matrix metalloproteinases, and a number of antioxidant genes are associated with accelerated FEV1 decline in COPD.
- Type
- article
- Published
- 2007-06-01
- Cited by
- 31
- References
- 28
- Access
- Open access
- OpenAlex
- https://openalex.org/W1481228586
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6086458
Keywords
COPD, Medicine, Genetic predisposition, Lung function, Disease
References
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- Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema.
- Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema.
- Oxidative stress indices in COPD--Broncho-alveolar lavage and salivary analysis.
- Genes, oxidative stress, and the risk of chronic obstructive pulmonary disease
- Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
- Smoking reduction and the rate of decline in FEV1: results from the Lung Health Study
- Genome-Wide RNAi Screen for Host Factors Required for Intracellular Bacterial Infection
- Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study.
- Association of lung function decline with the heme oxygenase-1 gene promoter microsatellite polymorphism in a general population sample. Results from the European Community Respiratory Health Survey (ECRHS), France
- Polymorphisms in the β2 adrenergic receptor and bronchodilator response, bronchial hyperresponsiveness, and rate of decline in lung function in smokers
- Bronchodilator response in the lung health study over 11 yrs
- Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers.
Cited by
- Association between baseline airflow obstruction and rate of decline in lung function.
- LUNG PHYSIOLOGY and AIRWAY INFLAMMATION INCOPD PATIENTS WITH PERSISTENT SPUTUM PRODUCTION
- Defining the Pulmonary Disease and Disability from Lung Dysfunction in Cutis Laxa
- Role of oxidative stress & transient receptor potential in chronic obstructive pulmonary disease
- Asthma and chronic obstructive pulmonary disease: common genes, common environments?
- Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD
- Serum Vitamin D in Patients with Chronic Obstructive Lung Disease Does Not Correlate with Mortality – Results from a 10-Year Prospective Cohort Study
- Lungenfunktion im Alter: Brauchen wir neue Referenzwerte?
- Pharmacogenetics in drug discovery and development: a translational perspective
- Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema.
- Time for new reference values for ventilatory lung function
- Antibiotic Therapy for Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
- Lung function in our aging population
- Asthma and COPD: Common Genes, Common Environments?
- Chronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research – a consensus document from six scientific societies
- Chronic obstructive pulmonary disease and risk factors-with reference to gender, socioeconomic status and educational levels: A hospital based study
- Diagnosis and Treatment of Early Chronic Obstructive Lung Disease (COPD)
- A Systematic Literature Review of the Humanistic Burden of COPD
- Bronchial gene expression signature associated with rate of subsequent FEV1 decline in individuals with and at risk of COPD
- Exosomes in chronic respiratory diseases.
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