Mitochondrial Dysfunction in Parkinson's Disease
Explore this paper's citation graph
Summary
Evidence for the roles of mitochondrial dysfunction and increased OS in the neuronal loss that leads to PD is examined and how this knowledge further improve the treatment for patients with PD is discussed.
- Type
- review
- Published
- 2015-06-01
- Cited by
- 336
- References
- 100
- Access
- Open access
- OpenAlex
- https://openalex.org/W826091804
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14740293
Keywords
Parkinson's disease, Disease, Medicine, Mitochondrial disease, Neuroscience
References
- Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice*
- Koenzym Q10 beim Morbus Parkinson
- Lack of evidence for an association between UCHL1 S18Y and Parkinson’s disease
- Chronic systemic pesticide exposure reproduces features of Parkinson's disease
- Lysosomal Impairment in Parkinson’s Disease
- Manganese ethylene‐bis‐dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction
- Expression of A53T Mutant But Not Wild-Type α-Synuclein in PC12 Cells Induces Alterations of the Ubiquitin-Dependent Degradation System, Loss of Dopamine Release, and Autophagic Cell Death
- Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship
- Lack of association between UCHL1 S18Y gene polymorphism and Parkinson’s disease in the Asian population: a meta-analysis
- Mesenchymal stem cells in osteobiology and applied bone regeneration.
- Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson’s disease
- A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2–q13.1
- Role of DJ-1 in parkinson’s disease
- Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology.
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- Mitochondrial Homeostasis Molecules: Regulation by a Trio of Recessive Parkinson's Disease Genes
- Mitochondrial Dysfunction of Immortalized Human Adipose Tissue-Derived Mesenchymal Stromal Cells from Patients with Parkinson's Disease
- MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transport.
- Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes
- Redox-Mediated Gene Therapies for Environmental Injury: Approaches and Concepts
Cited by
- Complex liaisons moving forward the Parkinson’s disease? An appraisal
- Mitochondrial genome changes and neurodegenerative diseases
- New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases
- Systems biology analysis of the proteomic alterations induced by MPP+, a Parkinson's disease-related mitochondrial toxin
- Biophysical Characterization of α-Synuclein and Rotenone Interaction
- Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins
- Global Stress Response in a Prokaryotic Model of DJ-1-Associated Parkinsonism
- Dietary fat intake and risk for Parkinson’s disease
- Cognitive Impairment Associated with Parkinson’s Disease: Role of Mitochondria
- Mitochondrial dysfunction in DDR-related cancer predisposition syndromes.
- Mic60/Mitofilin Overexpression Alters Mitochondrial Dynamics and Attenuates Vulnerability of Dopaminergic Cells to Dopamine and Rotenone
- V63 and N65 of overexpressed α-synuclein are involved in mitochondrial dysfunction.
- Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling.
- Phytochemicals as future drugs for Parkinson’s disease: a comprehensive review
- A promising therapeutic potential of cerebrolysin in 6-OHDA rat model of Parkinson's disease.
- Valproate-Associated Parkinsonism: A Critical Review of the Literature
- Mutational scanning of the CHCHD2 gene in Han Chinese patients with Parkinson's disease and meta-analysis of the literature.
- Mutational analysis of CHCHD2 in Chinese patients with multiple system atrophy and amyotrophic lateral sclerosis.
- Neuroprotection comparison of chlorogenic acid and its metabolites against mechanistically distinct cell death-inducing agents in cultured cerebellar granule neurons.
- The Skin and Parkinson's Disease: Review of Clinical, Diagnostic, and Therapeutic Issues
Related papers
- Usefulness of Parkinson's KinetiGraph in a Parkinson's disease clinic – Survey of 82 patients
- 薬剤性Parkinson症候群 (7月第1土曜特集 Parkinson病) -- (Parkinson症候群)
- Analysis on the Effect of Heavy Metals and Genetics on the Prevalence of Parkinson’s Disease
- Parkinson’s Disease-Overview
- [The experimental models of Parkinson's disease in animals].
- Characteristics, treatment patterns and disease burden of people with Parkinson's disease in the Parkinson's disease real-world impact assessment (PRISM) study
- Non-Alcoholic Fatty Liver Disease: Current Perspectives and Future Direction in Disease pathogenesis, Treatment and Diagnosis
- MicroRNAs as mediators of cardiovascular disease: Targets to be manipulated.
- Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease