Mitochondria and heart disease.
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Summary
Specific mitochondrial cardiomyopathies due to mutations in mtDNA have been identified, usually in a gene for a tRNA, which, although rare, are almost always very severe once the mutation has exceeded its threshold.
- Type
- review
- Published
- 2012-01-01
- Cited by
- 104
- References
- 152
- OpenAlex
- https://openalex.org/W308464728
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13209672
Keywords
Mitochondrial permeability transition pore, Mitochondrion, Cardioprotection, MPTP, Mitochondrial disease
References
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- Respiratory control in the glucose perfused heart
- Inhibition of the mitochondrial calcium uniporter by the oxo‐bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart
- Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion.
- Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
- Time-dependent changes in canine cardiac mitochondrial function and ultrastructure resulting from coronary occlusion and reperfusion
- The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms.
Cited by
- Emotional Triggering of Cardiac Dysfunction: The Present and Future
- Structural damage to the enteric nervous system following ischemia / reperfusion injury
- Kaempferol protects cardiomyocytes against anoxia/reoxygenation injury via mitochondrial pathway mediated by SIRT1.
- Regulation of Cytochrome C Oxidase Composition by Oxygen and Oxidative Stress
- Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects
- The expression characteristics of mt-ND2 gene in chicken
- Mitochondrial flash as a novel biomarker of mitochondrial respiration in the heart.
- Myofibroblast-mediated mechanisms of pathological remodelling of the heart
- Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy
- Implication of bidirectional promoters containing duplicated GGAA motifs of mitochondrial function-associated genes
- The effects of quercetin protect cardiomyocytes from A/R injury is related to its capability to increasing expression and activity of PKCε protein
- Ketone bodies and two-compartment tumor metabolism: Stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells
- Long‐term Aβ exposure augments mCa2+‐independent mROS‐mediated depletion of cardiolipin for the shift of a lethal transient mitochondrial permeability transition to its permanent mode in NARP cybrids: a protective targeting of melatonin
- Mitochondria and Reactive Oxygen Species: Physiology and Pathophysiology
- Calcium signaling in cardiac mitochondria
- Confocal Imaging of Single Mitochondrial Superoxide Flashes in Intact Heart or in vivo
- Estrogen-Related Receptor α (ERRα) and ERRγ Are Essential Coordinators of Cardiac Metabolism and Function
- Adrenergic Signaling Regulates Mitochondrial Ca2+ Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca2+ Uniporter
- A dynamic interface between vacuoles and mitochondria in yeast.
- Roles of Calcium Regulating MicroRNAs in Cardiac Ischemia-Reperfusion Injury
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