The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas
Explore this paper's citation graph
- Type
- article
- Published
- 2008-10-15
- Cited by
- 27
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W307584068
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:28807912
Keywords
Oncogene, Ovarian cancer, Cancer research, Cancer, Library science
References
- High resolution analysis of genomic aberrations by metaphase and array comparative genomic hybridization identifies candidate tumour genes in lung cancer cell lines.
- Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours
- Telomere dysfunction, genome instability and cancer.
- The ZNF217 gene amplified in breast cancers promotes immortalization of human mammary epithelial cells.
- Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer.
- Expression of protein elongation factor eEF1A2 predicts favorable outcome in breast cancer
- Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix.
- Moonlighting Functions of Polypeptide Elongation Factor 1: From Actin Bundling to Zinc Finger Protein R1-Associated Nuclear Localization
- Identification of Genes Directly Regulated by the Oncogene ZNF217 Using Chromatin Immunoprecipitation (ChIP)-Chip Assays*
- Modulation of translation factor's gene expression by histone deacetylase inhibitors in breast cancer cells
- Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer
- RNA-mediated response to heat shock in mammalian cells
- Differentially Regulated Genes as Putative Targets of Amplifications at 20q in Ovarian Cancers
- Amplification and overexpression of Aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells
- eEF1A2 activates Akt and stimulates Akt-dependent actin remodeling, invasion and migration
- Peptide Elongation Factor eEF1A-2/S1 Expression in Cultured Differentiated Myotubes and Its Protective Effect against Caspase- 3-mediated Apoptosis*
- Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence
- Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression
- Mouse translation elongation factor eEF1A‐2 interacts with Prdx‐I to protect cells against apoptotic death induced by oxidative stress
- Genetic and cytogenetic observations among different types of ovarian tumors are compatible with a progression model underlying ovarian tumorigenesis.
Cited by
- From global phosphoproteomics to individual proteins: the case of translation elongation factor eEF1A
- The eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral Infections
- Proteomic analysis of trichloroethylene-induced alterations in expression, distribution, and interactions of SET/TAF-Iα and two SET/TAF-Iα-binding proteins, eEF1A1 and eEF1A2, in hepatic L-02 cells.
- Eef1a2 Promotes Cell Growth, Inhibits Apoptosis and Activates JAK/STAT and AKT Signaling in Mouse Plasmacytomas
- The ZNF217 oncogene is a candidate organizer of repressive histone modifiers
- ZNF217 is a marker of poor prognosis in breast cancer that drives epithelial-mesenchymal transition and invasion.
- ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells
- Recurrent genomic alterations in benign and malignant pheochromocytomas and paragangliomas revealed by whole-genome array comparative genomic hybridization analysis.
- Comparative transcriptome pairwise analysis of spontaneously transformed multipotent stromal cells from human adipose tissue
- Microarray analysis of gene expression in the ovarian cancer cell line HO-8910 with silencing of the ZNF217 gene.
- ERRγ target genes are poor prognostic factors in Tamoxifen-treated breast cancer
- Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia
- The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value
- Regulating the expression of eEF1A to decipher its non canonical functions in eukaryotic cells
- Characterization of novel peptide-specific antibodies against the translation elongation factor eEF1A2 and their application for cancer research
- Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress
- Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival
- LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway
- ZNF217: the cerberus who fails to guard the gateway to lethal malignancy.
- Neuroblastoma Cell Death Induced by eEF1A2 Knockdown Is Possibly Mediated by the Inhibition of Akt and mTOR Phosphorylation
Related papers
- BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells
- Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling
- Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer