Immunosuppressive drugs, immunophilins, and functional expression of NCX isoforms.

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Summary

It is shown now that the large cytosolic loop of NCX1, NCX2, and NCX3 is involved in acquisition of immunosuppressive drug specificity: truncation of theLarge cytosol loop ofNCX1 renders the protein sensitive to FK506.

Type
review
Published
2013-01-01
Cited by
4
References
76

Keywords

FKBP, Cypa, HEK 293 cells, Chemistry, Cyclophilin A

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