Role of focal adhesion kinase in signaling by the extracellular matrix.

Keywords

Cell biology, Biology, Integrin, Vinculin, Focal adhesion

References

• Integrins: versatility, modulation, and signaling in cell adhesion.茂樹 角永, 毅 中井, 博伸 坂浦 — 1992
• p130Cas, a Substrate Associated with v-Src and v-Crk, Localizes to Focal Adhesions and Binds to Focal Adhesion Kinase*淳 鷲尾, 聰一 畑, 清水 新井 — 1996
• Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and AktIraklis Hatziathanasiou, Colin McLaren — 1997
• The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesionsBalbina Martínez Caviró — 1997
• Differential roles of PI3‐kinase and Kit tyrosine 821 in Kit receptor‐mediated proliferation, survival and cell adhesion in mast cells.Hubert Serve, Nelson S. Yee, Giulia Maria Stella — 1995
• Targeted proteolysis of the focal adhesion kinase pp125 FAK during c-MYC-induced apoptosis is suppressed by integrin signalling.D H Crouch, Valerie J. Fincham, Margaret C. Frame — 1996
• Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.Lori J. Kornberg, H. Shelton Earp, J. Thomas Parsons — 1992
• Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase.Stefan Wennström, Agneta Siegbahn, Koutaro Yokote — 1994
• Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensin.Susanne M. Bockholt, Keith Burridge — 1993
• Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells.Carolyn M. Kapron‐Brás, L Fitz-Gibbon, P. JEEVARATNAM — 1993
• Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain.Matvey Lukashev, Dean Sheppard, Robert Pytela — 1994
• A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK.Peter Chan, Steven B. Kanner, Gena S. Whitney — 1994
• Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.James Sinnett‐Smith, Ian Zachary, Ángela M. Valverde — 1993
• Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60srcMichael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon — 1994
• Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinasesKristiina Vuori, Hisamaru Hirai, Shinichi Aizawa — 1996
• A novel signaling molecule, p130, forms stable complexes in vivo with v‐Crk and v‐Src in a tyrosine phosphorylation‐dependent manner.Ryuichi Sakai, Akihiro Iwamatsu, Naoto Hirano — 1994
• CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cellsMichiyuki Matsuda, Yuko Hashimoto, Kenkoh Muroya — 1994
• Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAKMichael D. Schaller, Cheryl A. Borgman, J. Thomas Parsons — 1993
• Extracellular Matrix Survival Signals Transduced by Focal Adhesion Kinase Suppress p53-mediated ApoptosisDuško Ilić, Eduardo A.C. Almeida, David D. Schlaepfer — 1998
• Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn.Leslie A. Cary, J Chang, Jun‐Lin Guan — 1996

Cited by

• Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression.David G. Schultz — 2003
• Focal adhesion kinase: protein interactions and cellular functions.Smita Abbi, Jun‐Lin Guan — 2002
• Relationship between focal adhesion kinase and hepatic stellate cell proliferation during rat hepatic fibrogenesis.Huiqing Jiang — 2004
• CLCA : chloride channel or modulator?Matthew E. Loewen — 2004
• Cell Motility in Cancer Invasion and MetastasisAlan Wells — 2006
• Elucidation of Pertussis Toxin-Sensitive Migration Signaling in Human Breast Cancer CellsWilliam L. Rust — 2001
• v-Src SH3-enhanced Interaction with Focal Adhesion Kinase at β1 Integrin-containing Invadopodia Promotes Cell Invasion*Christof R. Hauck, Datsun A. Hsia, Duško Ilić — 2002
• The ins and outs of fibronectin matrix assemblyIwona Wierzbicka‐Patynowski, Jean E. Schwarzbauer — 2003
• Regulatory Role for Src and Phosphatidylinositol 3-Kinase in Initiation of Fibronectin Matrix Assembly*Iwona Wierzbicka‐Patynowski, Jean E. Schwarzbauer — 2002
• A novel RGD-toxin protein, Lj-RGD3, from the buccal gland secretion of Lampetra japonica impacts diverse biological activities.Jihong Wang, Xiaoxi Han, Hsinshen Yang — 2010
• Continuous requirement for pp60‐Src and phospho‐paxillin during fibronectin matrix assembly by transformed cellsIwona Wierzbicka‐Patynowski, Yong Mao, Jean E. Schwarzbauer — 2007
• The Promise of Integrins as Effective Targets for Anticancer AgentsWilliam L. Rust, Stephen W. Carper, George E. Plopper — 2002
• Regulation of Focal Adhesion Kinase by Its Amino-Terminal Domain through an Autoinhibitory InteractionLee Ann Cooper, Tang‐Long Shen, Jun‐Lin Guan — 2003
• Akt1 Signaling Regulates Integrin Activation, Matrix Recognition, and Fibronectin Assembly*Payaningal R. Somanath, Eugene Kandel, Nissim Hay — 2007
• Involvement of apoptosis in progression of cochlear lesion following exposure to intense noise.Bo Hua Hu, Donald Henderson, Thomas M. Nicotera — 2002
• Focal Adhesion Kinase Activated by β4 Integrin Ligation to mCLCA1 Mediates Early Metastatic Growth*Mossaad Abdel‐Ghany, Hung-Chi Cheng, Randolph C. Elble — 2002
• FRNK blocks v‐Src‐stimulated invasion and experimental metastases without effects on cell motility or growthChristof R. Hauck, Datsun A. Hsia, Xose S. Puente — 2002
• Residues within the First Subdomain of the FERM-like Domain in Focal Adhesion Kinase Are Important in Its Regulation*Lee Ann Cohen, Jun‐Lin Guan — 2005
• Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasisDebarati Mukherjee, Heng Lu, Lin Yu — 2016
• Role of KLF8-CXCR4 signaling in Breast Cancer MetastasisDebarati Mukherjee — 2016

Related papers

• Specific decrease in the level of Hic‐5, a focal adhesion protein, during immortalization of mouse embryonic fibroblasts, and its association with focal adhesion kinaseKeiko Ishino, Joo-ri Kim Kaneyama, Motoko Shibanuma — 2000
• Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruptionJochen Kirchner, Zvi Kam, Gila Tzur — 2003
• pp125FAK tyrosine kinase activity is not required for the assembly of F-actin stress fibres and focal adhesions in cultured mouse aortic smooth muscle cells.Lynn Wilson, Martin Carrier, Stuart Kellie — 1995
• Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigrationSean A. Parsons, Ritu Sharma, Dawn Louise Roccamatisi — 2012
• FAAP, a novel murine protein, is involved in cell adhesion through regulating vinculin-paxillin association.Jinsong Hu — 2008
• Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesionsEileen Crowley, Alan F. Horwitz — 1995
• Cell–Material Interplay in Focal Adhesion PointsKrzysztof Berniak, Daniel P. Ura, Adam Piórkowski — 2024
• The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-delta to focal adhesions.Simon T. Barry, David R. Critchley — 1994
• pp125FAK in the focal adhesion.Carol Otey — 1996