Neuroplastic alterations in the limbic system following cocaine or alcohol exposure.

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Summary

Evidence that drugs of abuse are powerful modulators of synaptic plasticity is reviewed, finding that dopaminergic neurons of the ventral tegmental area as well as medium spiny neurons in nucleus accumbens show enhanced excitatory synaptic strength following passive or active exposure to drugs such as cocaine and alcohol.

Type
review
Published
2010-01-01
Cited by
69
References
202

Keywords

Neuroscience, Ventral tegmental area, Nucleus accumbens, Synaptic plasticity, Metaplasticity

References

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