The nucleosome: from genomic organization to genomic regulation.
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Summary
This review focuses on the conserved protein structures that mobilize and remodel nucleosomes and specifically mark and recognize their histone and DNA components.
- Type
- review
- Published
- 2004-01-23
- Cited by
- 717
- References
- 122
- Access
- Open access
- OpenAlex
- https://openalex.org/W160911776
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15504162
Keywords
Nucleosome, Biology, Histone, Genome, DNA replication
References
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- Structure and ligand of a histone acetyltransferase bromodomain
- Position and orientation of the globular domain of linker histone H5 on the nucleosome
- Crystal structure of a nucleosome core particle containing the variant histone H2A.Z
- Sir2 links chromatin silencing, metabolism, and aging.
- Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
- Cooperation between complexes that regulate chromatin structure and transcription.
- Chromatin sub-structure. The digestion of chromatin DNA at regularly spaced sites by a nuclear deoxyribonuclease.
- Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA.
- Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
- Structural analysis of the yeast SWI/SNF chromatin remodeling complex
- Structure of histone deacetylases: insights into substrate recognition and catalysis.
- Deciphering the transcriptional histone acetylation code for a human gene.
- DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139*
Cited by
- Inhibition of iNOS expression and NO production by anti-inflammatory steroids. Reversal by histone deacetylase inhibitors.
- Histone modifications: from genome-wide maps to functional insights
- Protein posttranslational modifications: the chemistry of proteome diversifications.
- Regulation of nucleosome stability as a mediator of chromatin function.
- Structural flexibility of the nucleosome core particle at atomic resolution studied by molecular dynamics simulation.
- Remodeling of higher order chromatin structure by the JIL-1 histone H3 kinase in Drosophila
- Synthesis of ε-N-propionyl-, ε-N-butyryl-, and ε-N-crotonyl-lysine containing histone H3 using the pyrrolysine system.
- Dynamic organization of chromatin assembly and transcription factories in living cells.
- Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation
- Involvement of rice histone deacetylase HDA705 in seed germination and in response to ABA and abiotic stresses.
- Clinical and Therapeutic Implications of Histone Acetylation in Breast Cancer.
- Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins
- Réorganisation de l'épigénome au cours de la spermiogénèse
- Molecular Genetic Studies of ALSG, Kostmann Syndrome and a Novel Chromosome 10 Inversion
- Brain Crosstalk in Puberty and Adolescence
- Epigenetic transcriptional repression of tumor suppresor genes and its reversion by drugs.
- Epigenetic mechanisms in AML - a target for therapy.
- Nuclear architecture and structural dynamics - molecular basis of chromatin remodeling induced by human ISWI machines -
- Caractérisation des interactions protéine / ligand par échange 1H/3H : application au complexe entre la protéine hAsf1 et l'histone H3
- Somatic cell nuclear transfer (SCNT) in mammals: the cytoplast and its reprogramming activities.
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