Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

Sushmita Roy, J F Ernst, Peter V. Kharchenko, Pouya Kheradpour, Nicolas Nègre · Science · 2010

Summary

Two studies identified regions of the nematode and fly genomes that show highly occupied targets (or HOT) regions where DNA was bound by more than 15 of the transcription factors analyzed and the expression of related genes were characterized.

Type: article
Published: 2010-12-01
Cited by: 834
References: 86
Access: Open access
DOI: https://doi.org/10.1126/science.1198374
PubMed: https://pubmed.ncbi.nlm.nih.gov/21177974/
PMC: https://www.ncbi.nlm.nih.gov/pmc/articles/3192495/
OpenAlex: https://openalex.org/W149228750
Semantic Scholar: https://api.semanticscholar.org/CorpusID:218756237

Keywords

Identification (biology), Drosophila (subgenus), Computer science, Computational biology, Biology

References

GENETICSJoseph H. Nadeau, Aimée M. Dudley — 2011
IL-13受体α2降低血吸虫病肉芽肿的炎症反应并延长宿主存活时间[英]/Mentink-Kane MM,Cheever AW，Thompson RW，et al//Proc Natl Acad Sci U S A姚利晓, 蔡幼民, 林矫矫 — 2005
This copy is for your personal, non-commercial use only.Seonhee Kim, W. Wadsworth — 2014

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Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

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