Necrotic cell death in Caenorhabditis elegans.
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Summary
This work overviews necrotic paradigms that have been characterized in the nematode and outlines the cellular and molecular mechanisms that mediate this mode of cell demise, and discusses experimental approaches that utilize C. elegans to elucidate the molecular underpinnings of devastating human disorders that entail necrosis.
- Type
- review
- Published
- 2014-01-01
- Cited by
- 20
- References
- 112
- OpenAlex
- https://openalex.org/W110631653
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40147149
Keywords
Caenorhabditis elegans, Biology, Programmed cell death, Cell biology, Caenorhabditis
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Cited by
- Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease
- Bacillus thuringiensis Crystal Protein Cry6Aa Triggers Caenorhabditis elegans Necrosis Pathway Mediated by Aspartic Protease (ASP-1)
- How are necrotic cells recognized by their predators?
- Caenorhabditis elegans as a powerful alternative model organism to promote research in genetic toxicology and biomedicine
- Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans
- Sensory cilia as the Achilles heel of nematodes when attacked by carnivorous mushrooms
- APP-Induced Patterned Neurodegeneration Is Exacerbated by APOE4 in Caenorhabditis elegans
- Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death
- Xenobiotic metabolism and transport in Caenorhabditis elegans
- Nuclear lipid droplets and nuclear damage in Caenorhabditis elegans
- Cell Death and Transcriptional Responses Induced in Larvae of the Nematode Haemonchus contortus by Toxins/Toxicants with Broad Phylogenetic Efficacy
- Novel Nematode-Killing Protein-1 (Nkp-1) from a Marine Epiphytic Bacterium Pseudoalteromonas tunicata
- Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins
- How do necrotic cells expose phosphatidylserine to attract their predators—What’s unique and what’s in common with apoptotic cells
- Live or death in cells: from micronutrition metabolism to cell fate
- Nematodes exposed to furfural acetone exhibit a species-specific vacuolar H+-ATPase response.
- Lytic coelomocyte death is tuned by cleavage but not phosphorylation of MLKL in echinoderms
- Potential impact of marine heatwaves on the survival and transcriptomic signature of free-living third-stage larvae (L3) of Anisakis simplex (Nematoda: Anisakidae)
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