Microbiota, inflammation and obesity.
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Summary
Current understanding of how gut microbiota could contribute to defining whole-body metabolism by influencing diverse components of the innate and adaptive immune system, both locally and systemically is discussed.
- Type
- review
- Published
- 2014-01-01
- Cited by
- 124
- References
- 98
- OpenAlex
- https://openalex.org/W104707605
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23308630
Keywords
Innate immune system, Inflammation, Gut flora, Immunology, Immune system
References
- Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance
- Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
- Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice
- Bacteroides uniformis CECT 7771 Ameliorates Metabolic and Immunological Dysfunction in Mice with High-Fat-Diet Induced Obesity
- A role for the NLRP3 inflammasome in metabolic diseases and did Warburg miss inflammation?
- Bifidobacterium CECT 7765 improves metabolic and immunological alterations associated with obesity in high‐fat diet‐fed mice
- Differential intestinal M‐cell gene expression response to gut commensals
- Enterocyte TLR4 Mediates Phagocytosis and Translocation of Bacteria Across the Intestinal Barrier
- Augmented hepatic Toll‐like receptors by fatty acids trigger the pro‐inflammatory state of non‐alcoholic fatty liver disease in mice
- The cellular and signaling networks linking the immune system and metabolism in disease
- Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus
- Regulation of Serum Amyloid A3 (SAA3) in Mouse Colonic Epithelium and Adipose Tissue by the Intestinal Microbiota
- Obesity alters gut microbial ecology.
- Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota.
- Association of Glutathione S-transferase genes (GSTM1 and GSTT1) polymorphisms with hypertension in lead-exposed workers
- Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice
- Blood Microbiota Dysbiosis Is Associated with the Onset of Cardiovascular Events in a Large General Population: The D.E.S.I.R. Study
- Absence of intestinal microbiota does not protect mice from diet-induced obesity
- Inflammation, Cytokines and Insulin Resistance: A Clinical Perspective
- Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish
Cited by
- Bugs, guts and brains, and the regulation of food intake and body weight.
- Interplay Between the Gut-Brain Axis, Obesity and Cognitive Function
- Immunonutrition: methodology and applications.
- Delivery by caesarean section and risk of childhood obesity: analysis of a Peruvian prospective cohort
- Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue
- Understanding the role of gut microbiome in metabolic disease risk
- Gut Microbiome and Obesity: A Plausible Explanation for Obesity
- Simulated microgravity disrupts intestinal homeostasis and increases colitis susceptibility
- The dormant blood microbiome in chronic, inflammatory diseases
- Metabolome of human gut microbiome is predictive of host dysbiosis
- GUT MICROBIOTA DYSBIOSIS IS LINKED TO HYPERTENSION
- Inflammatory markers and cardiometabolic diseases
- The human gut microbial ecology associated with overweight and obesity determines ellagic acid metabolism.
- A Novel Small Molecule Drug Derived from Methimazole (Phenylmethimazole) that Targets Aberrant Toll-like Receptor Expression and Signaling for the Potential Prevention or Treatment of Diabetes Mellitus and Non-alcoholic Fatty Liver Disease
- Obesity-Driven Gut Microbiota Inflammatory Pathways to Metabolic Syndrome
- Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes.
- Differential Analysis of the Nasal Microbiome of Pig Carriers or Non-Carriers of Staphylococcus aureus
- Cerebrospinal Fluid Biomarkers in Highly Exposed PM2.5 Urbanites: The Risk of Alzheimer’s and Parkinson’s Diseases in Young Mexico City Residents
- Impact of polyphenols combined with high-fat diet on rats' gut microbiota
- Does obesity influence the subgingival microbiota composition in periodontal health and disease?
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