The neuropathological diagnosis of Alzheimer disease.
Explore this paper's citation graph
Summary
The role of plaques and tangles in the pathogenesis of AD and their relationship to both neuronal loss and dementia remain to be elucidated, clinicopathological studies have shown that both lesions, if present in sufficient numbers, are considered the best correlates for AD related dementia.
- Type
- review
- Published
- 1998-01-01
- Cited by
- 61
- References
- 92
- OpenAlex
- https://openalex.org/W83011722
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45430318
Keywords
Neurology, Medicine, Neuroscience, Disease, Neuropathology
References
- A cellular mechanism for the neuronal changes underlying Alzheimer's disease.
- Alzheimer's disease : advances in clinical and basic research
- Making the diagnosis of Alzheimer's disease. A primer for practicing pathologists.
- Research advances in Alzheimer's disease and related disorders
- Alzheimer disease, from molecular biology to therapy.
- Plaques, tangles and dementia. A quantitative study.
- “Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician
- Cholinergic fibre loss associated with diffuse plaques in the non-demented elderly: the preclinical stage of Alzheimer’s disease?
- Interlaboratory Histopathologic Assessment of Alzheimer Neuropathology: Different Methodologies Yield Comparable Diagnostic Results
- Cell cycle markers in the hippocampus in Alzheimer’s disease
- Relative roles of plaques and tangles in the dementia of Alzheimer's disease: correlations using three sets of neuropathological criteria.
- Staging of Alzheimer-type pathology: an interrater-intrarater study.
- CLINICOPATHOLOGIC CORRELATIONS OF THE ALZHEIMERʼS DISEASE STAGING SYSTEM INTRODUCED BY BRAAK AND BRAAK
- Neuropathologic Diagnosis of Alzheimer Disease: Interrater Reliability in the Assessment of Senile Plaques and Neurofibrillary Tangles
- The cholinergic system in Alzheimer's disease.
- Relationship between plaques, tangles, and dystrophic processes in Alzheimer's disease.
- Qualitative and Quantitative Differences in Senile Plaque Dystrophie Neurites of Alzheimer's Disease and Normal Aged Brain
- Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference
- Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
- Accuracy of Clinical Diagnosis of Alzheimer Disease and Clinical Features of Patients with Non-Alzheimer Disease Neuropathology
Cited by
- How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes
- Age-related neuropathology, cognitive decline, and Alzheimer's disease.
- Endocrine and diagnostic aspects of cognitive impairment
- The Role of Insulin Resistance in the Pathogenesis of Alzheimer’s Disease
- The effects of soluble Aβ oligomers on neurodegeneration in Alzheimer's disease.
- Phosphorylated amyloid-beta: the toxic intermediate in alzheimer's disease neurodegeneration.
- Age-related intraneuronal accumulation of αII-spectrin breakdown product SBDP120 in the human cerebrum is enhanced in Alzheimer's disease.
- Assessing p97 as an Alzheimer's disease serum biomarker
- Expanding the Model of Apathy in Parkinson's Disease: Exploration of Conceptual Domains and Identification of Neuropsychological Correlates
- Biologic models of neurodegenerative disorders.
- Interactions between occlusion and human brain function activities.
- The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: an update
- Role of Hydrogen Peroxide in the Aetiology of Alzheimer’s Disease
- Association of estrogen receptor alpha gene with Alzheimer's disease: a case-control study.
- The Role of Higher-Level Cognitive Function in Gait: Executive Dysfunction Contributes to Fall Risk in Alzheimer’s Disease
- Imaging beta-amyloid fibrils in Alzheimer's disease: a critical analysis through simulation of amyloid fibril polymerization.
- Neuronal Production of Transthyretin in Human and Murine Alzheimer’s Disease: is it Protective?
- Role of the Immune System in the Pathogenesis, Prevention and Treatment of Alzheimer’s Disease
- Exploring a Mathematical Model for the Kinetics of β-Amyloid Molecular Imaging Probes through a Critical Analysis of Plaque Pathology
- The up‐regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α
Related papers
- Genentech taps Affimed’s antibodies
- KOMPLIKASI REGIONAL ANESTESI PADA PEDIATRIK
- Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria
- Cardiac retransplantation in children.
- Avaliacao hemodinamica sequencial em transplante de coracao
- Thoracoscopic discectomy and fusion in the treatment of spinal deformities
- [The current status of neuropathology in the Federal Republic of Germany 1979 (author's transl)].
- [Hepatic retransplant and acute Budd Chiari syndrome. Case report].