Cross-presentation of cell-associated antigens by dendritic cells.
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Summary
Exogenous pathways of MHC class I-restricted antigen presentation play an important role in the generation of antiviral immunity, particularly in the immune surveillance of virus-infected tissues of nonhematopoietic origin.
- Type
- review
- Published
- 2003-01-01
- Cited by
- 49
- References
- 62
- OpenAlex
- https://openalex.org/W65670449
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12125305
Keywords
Antigen presentation, Cross-presentation, Immunity, Antigen, Immunology
References
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- Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
- Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells
- Cutting Edge: Intravenous Soluble Antigen Is Presented to CD4 T Cells by CD8− Dendritic Cells, but Cross-Presented to CD8 T Cells by CD8+ Dendritic Cells1
- Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules.
- Mature dendritic cells pulsed with freeze-thaw cell lysates define an effective in vitro vaccine designed to elicit EBV-specific CD4(+) and CD8(+) T lymphocyte responses.
- Phagosomes are fully competent antigen-processing organelles that mediate the formation of peptide:class II MHC complexes.
- Human Cytomegalovirus pp65- and Immediate Early 1 Antigen-Specific HLA Class I-Restricted Cytotoxic T Cell Responses Induced by Cross-Presentation of Viral Antigens1
- Cross-tolerance: A Pathway for Inducing Tolerance to Peripheral Tissue Antigens
- Poxvirus as a vector to transduce human dendritic cells for immunotherapy: abortive infection but reduced APC function
- Receptor-Mediated Uptake of Antigen/Heat Shock Protein Complexes Results in Major Histocompatibility Complex Class I Antigen Presentation via Two Distinct Processing Pathways
- In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter.
- Inhibition of dendritic cell maturation by herpes simplex virus
- Dendritic cells resurrect antigens from dead cells.
- Class I‐restricted presentation of exogenous antigen acquired by Fcγ receptor‐mediated endocytosis is regulated in dendritic cells
- Efficiency of cross presentation of vaccinia virus‐derived antigens by human dendritic cells
Cited by
- Challenges in dendritic cells-based therapeutic vaccination in HIV-1 infection Workshop in dendritic cell-based vaccine clinical trials in HIV-1.
- Current Advances in Virus-Like Particles as a Vaccination Approach against HIV Infection
- Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies
- Involvement of dendritic cells in the pathogenesis of inflammatory bowel disease.
- L'Adenosina Desaminasa i les α-Defensines com a moduladors de respostes immunitàries front al VIH
- Effects on Innate Immunity of a Therapeutic Dendritic Cell-Based Vaccine for HIV-1 Infection
- Restoration by IL-15 of MHC Class I Antigen-Processing Machinery in Human Dendritic Cells Inhibited by Tumor-Derived Gangliosides1
- A subset of human plasmacytoid dendritic cells expresses CD8α upon exposure to herpes simplex virus type 1
- Characterization of the cytokine profile in adults with latent and active tuberculosis from a high endemic country
- Assessment of migration of HIV-1-loaded dendritic cells labeled with 111In-oxine used as a therapeutic vaccine in HIV-1-infected patients.
- In Vitro Priming Recapitulates In Vivo HIV-1 Specific T Cell Responses, Revealing Rapid Loss of Virus Reactive CD4+ T Cells in Acute HIV-1 Infection
- Dendritic cell based vaccines for HIV infection
- mRNA Is an Endogenous Ligand for Toll-like Receptor 3*
- Manipulation of dendritic cell functions by human cytomegalovirus
- Identifying the epitope-specific T cell response to virus infections.
- HIV-antigens charged on phosphorus dendrimers as tools for tolerogenic dendritic cells-based immunotherapy.
- A strategy for efficient cross-presentation of CTL-epitope peptides leading to enhanced induction of in vivo tumor immunity.
- Involvement of intestinal dendritic cells in oral tolerance, immunity to pathogens, and inflammatory bowel disease
- DC-virus interplay: a double edged sword.
- A Dendritic Cell–Based Vaccine Elicits T Cell Responses Associated with Control of HIV-1 Replication
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