Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.
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Summary
The impaired insulin secretion in Type 2 diabetes may be due to a decrease in B-cells and to disruption of the islet structure by amyloid, and the increase in A-cells may contribute to the hyperglucagonaemia and hyperglycaemia of Type 2 Diabetes.
- Type
- article
- Published
- 1988-12-01
- Cited by
- 575
- References
- 0
- OpenAlex
- https://openalex.org/W56426715
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23938298
Keywords
Internal medicine, Endocrinology, Islet, Diabetes mellitus, Pancreas
References
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