Clinically Relevant Drug-Drug and Drug-Food Interactions
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Summary
The main mechanisms involved in clinically relevant drug-drug and drug-food interactions are discussed and some of the studies used to predict them during drug development are outlined, including phase I metabolic reactions and the important role played by drug transporter proteins.
- Type
- article
- Published
- 2013-02-05
- Cited by
- 13
- References
- 130
- OpenAlex
- https://openalex.org/W44650606
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8033782
Keywords
Drug, Drug interaction, Pharmacology, Pharmacogenomics, Pharmacodynamics
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Cited by
- Drug interactions result from a number of underlying pharmacokinetic and pharmacodynamic mechanisms
- Catastrophic drug-drug interactions in psychopharmacology
- The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo
- The Crossroads of Aging
- Metabolism of a New Antiaggregant, Indolinone Derivative
- Interacciones farmacológicas potenciales en pacientes ambulatorios en expedientes de queja médica de la CONAMED
- CYP1A2 mRNA Expression Rather than Genetic Variants Indicate Hepatic CYP1A2 Activity
- CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients
- Knowledge, attitude and practice (KAP) on food-drug interaction (FDI) among pharmacists working in government health facilities in Sabah, Malaysia
- Mini Review: Pharmacokinetics Changes During Childhood, Old Age and Pregnancy
- Science‐based anti‐ageing nutritional recommendations
- Clinical Relevance of Medicinal Plants and Foods of Vegetal Origin on the Activity of Cytochrome P450