RESTORATION OF MOTOR AND NON-MOTOR FUNCTIONS BY NEUROTROPHIC FACTORS IN NONHUMAN PRIMATES WITH DOPAMINE DEPLETION
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Summary
CDNF, N2 and N4 trophic factors are neurorestorative to DA neurons, motor function is tightly correlated with DA neuronal number, and N 4 improved the non-motor symptom of increased daytime sleepiness in this monkey PD model.
- Type
- article
- Published
- 2013-12-16
- Cited by
- 3
- References
- 487
- Access
- Open access
- OpenAlex
- https://openalex.org/W41886693
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:140924159
Keywords
MPTP, Glial cell line-derived neurotrophic factor, Dopamine, Neurotrophic factors, Neurturin
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Cited by
- Neuroregeneration in Parkinson’s Disease: From Proteins to Small Molecules
- Glial cell line-derived neurotrophic factors (GFLs) and small molecules targeting RET receptor for the treatment of pain and Parkinson’s disease
- CDNF Exerts Anxiolytic, Antidepressant-like, and Procognitive Effects and Modulates Serotonin Turnover and Neuroplasticity-Related Genes
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