Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease
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Summary
There is a transient increase of the expression of certain inhibitory receptors like LAG-3 and TIM-3 in COVID-19 in the overall context of acute immune activation.
- Type
- article
- Published
- 2020-08-26
- Cited by
- 63
- References
- 77
- Access
- Open access
- OpenAlex
- https://openalex.org/W32983106
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:221299836
Keywords
Isolator, Vibration isolation, Control theory (sociology), Inertia, Work (physics)
References
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- The TIGIT/CD226 axis regulates human T cell function
- T-bet:Eomes Balance, Effector Function and Proliferation of CMV-specific CD8+ T-cells during Primary Infection Differentiates the Capacity for Durable Immune Control
- Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
- Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation
- Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
- PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
- Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution
- T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection
- Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells
- IL-7 is critical for homeostatic proliferation and survival of naïve T cells
- Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection
- Characterization of T-Bet and Eomes in Peripheral Human Immune Cells
- CTLA‐4‐dependent mechanisms prevent T cell induced‐liver pathology during the erythrocyte stage of Plasmodium berghei malaria
- Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus Infection
- Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells.
- T-bet represses expression of PD-1 and sustains virus-specific CD8 T cell responses during chronic infection
- Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo
Cited by
- B cell analysis in SARS-CoV-2 versus malaria: Increased frequencies of plasmablasts and atypical memory B cells in COVID-19
- SARS-CoV-2: From the pathogenesis to potential anti-viral treatments
- Toward an understanding of regulatory T cells in COVID‐19: A systematic review
- Demystifying Excess Immune Response in COVID-19 to Reposition an Orphan Drug for Down-Regulation of NF-κB: A Systematic Review
- Immune Profile in Patients With COVID-19: Lymphocytes Exhaustion Markers in Relationship to Clinical Outcome
- Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment
- Evaluation of Th1 and Th2 mediated cellular and humoral immunity in patients with COVID-19 following the use of melatonin as an adjunctive treatment
- The Role of B and T Lymphocyte Attenuator in Respiratory System Diseases
- Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
- Physical activity and exercise as an essential medical strategy for the COVID-19 pandemic and beyond
- Interplay between Neutrophils, NETs and T-Cells in SARS-CoV-2 Infection—A Missing Piece of the Puzzle in the COVID-19 Pathogenesis?
- Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19
- Screening key genes and signaling pathways in COVID-19 infection and its associated complications by integrated bioinformatics analysis
- Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations
- Inhibitory Immune Checkpoint Molecules and Exhaustion of T cells in COVID-19
- Low incidence of COVID-19 case severity and mortality in Africa; Could malaria co-infection provide the missing link?
- Immunomodulatory Potential of Non-Classical HLA-G in Infections including COVID-19 and Parasitic Diseases
- Activated CD8+CD38+ Cells Are Associated With Worse Clinical Outcome in Hospitalized COVID-19 Patients
- Inhibitory Immune Checkpoint Receptors and Ligands as Prognostic Biomarkers in COVID-19 Patients
- CD8+ T Cells in SARS-CoV-2 Induced Disease and Cancer—Clinical Perspectives
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