Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma
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Summary
Results indicate that AR at least partially induced glycolysis via p-CREB regulation of HK2 in HCC cells, and this pathway should be considered for the design of novel therapeutic methods to target AR-overexpressing HCC.
- Type
- article
- Published
- 2020-04-09
- Cited by
- 20
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W32274668
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:215564924
Keywords
Quality (philosophy), Philosophy
References
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Cited by
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- Effects of crustacean hyperglycaemic hormone RNA interference on regulation of glucose metabolism in Litopenaeus vannamei after ammonia-nitrogen exposure
- LINC00941 promotes glycolysis in pancreatic cancer by modulating the Hippo pathway
- Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma
- MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis
- Why may citrate sodium significantly increase the effectiveness of transarterial chemoembolization in hepatocellular carcinoma?
- Regulation of Gamma-Aminobutyric Acid Transaminase Expression and Its Clinical Significance in Hepatocellular Carcinoma
- Emerging therapies for autosomal dominant polycystic kidney disease with a focus on cAMP signaling
- Metabolic changes during prostate cancer development and progression
- Multifaceted roles of aerobic glycolysis and oxidative phosphorylation in hepatocellular carcinoma
- Identification of key genes in hepatocellular carcinoma associated with exposure to TCDD and α-endosulfan by WGCNA.
- The Promoting Role of HK II in Tumor Development and the Research Progress of Its Inhibitors
- RON receptor tyrosine kinase regulates glycolysis through MAPK/CREB signaling to affect ferroptosis and chemotherapy sensitivity of thyroid cancer cells
- Duplicate CgCREBL2β involved in the response of oyster upon high-temperature stress through the induction of glycolysis and haemocyte apoptosis.
- Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
- Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma
- Molecular network of metabolic reprogramming and precision diagnosis and treatment of hepatocellular carcinoma
- Carbohydrate metabolism in prostate cancer
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