Myeloid malignancies with somatic GATA2 mutations can be associated with an immunodeficiency phenotype
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Summary
It is concluded that similar to germline GATA2 mutations, a subset of somatic Gata2 mutations can impart a germline phenotype.
- Type
- article
- Published
- 2019-01-16
- Cited by
- 17
- References
- 49
- OpenAlex
- https://openalex.org/W30648453
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:58602322
Keywords
Ex-ante, Economics
References
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Cited by
- Allogeneic hematopoietic cell transplantation in the management of GATA2 deficiency and pulmonary alveolar proteinosis.
- Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes
- Integrative Genomic Analysis Reveals Cancer-Associated Gene Mutations in Chronic Myeloid Leukemia Patients with Resistance or Intolerance to Tyrosine Kinase Inhibitor
- Human GATA2 mutations and hematologic disease: how many paths to pathogenesis?
- 基于二代测序技术分析酪氨酸激酶抑制剂耐药或不耐受慢性髓性白血病患者的肿瘤相关基因突变
- From Basic Biology to Patient Mutational Spectra of GATA2 Haploinsufficiencies: What Are the Mechanisms, Hurdles, and Prospects of Genome Editing for Treatment
- Somatic GATA2 mutations define a subgroup of myeloid malignancy patients at high risk for invasive fungal disease.
- Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes
- GATA2 rs2335052 and GATA2 rs78245253 single‐nucleotide polymorphisms in Chinese patients with acute myelocytic leukemia
- ASXL1 and STAG2 are common mutations in GATA2 deficiency patients with bone marrow disease and myelodysplastic syndrome
- Multiple Simultaneous Infections With Nontuberculous Mycobacteria in the Setting of GATA2 Mutation and Myelodysplastic Syndrome
- The Clinical Spectrum, Diagnosis, and Management of GATA2 Deficiency
- Identification and confirmation via in situ hybridization of Merkel cell polyomavirus in rare cases of posttransplant cutaneous T‐cell lymphoma
- A novel GATA2 distal enhancer mutation results in MonoMAC syndrome in 2 second cousins
- A 40-Year-Old With Prior Stem Cell Transplant for Chronic Myeloid Leukemia Presents With Dyspnea and Respiratory Failure
- Impact of baseline genetic profile and treatment on outcome and hematological toxicity in CEBPA-mutated AML
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