PDGFRβ Cells Rapidly Relay Inflammatory Signal from the Circulatory System to Neurons via Chemokine CCL2.
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Summary
It is shown that within 2 hr of systemic inflammation, PDGFRβ mural cells of blood vessels rapidly secrete chemokine CCL2, which in turn increases total neuronal excitability by promoting excitatory synaptic transmission in glutamatergic neurons of multiple brain regions.
- Type
- article
- Published
- 2018-10-01
- Cited by
- 194
- References
- 102
- Access
- Open access
- OpenAlex
- https://openalex.org/W30269986
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52894627
Keywords
Political science, Humanities, Art
References
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