Structural and functional studies of mannose binding lectin (MBL) and the lectin pathway of complement in children with cancer.

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Summary

Evidence is provided that MBL deficiency increases the frequency and the duration of FN in the largest paediatric cancer cohort studied to date, and individuals in possession of MBL variant alleles suffered from more frequent and longer episodes of FN over the study period.

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2008-01-01
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