MBL2 polymorphism and risk of severe infections in multiple myeloma patients receiving high-dose melphalan and autologous stem cell transplantation
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Summary
It is indicated that Mannan-binding lectin to some extent protects against the most severe infections during ASCT, and individuals homozygous for wild-type MBL encoding gene (MBL2) have a well-functioning MBL pathway of complement activation.
- Type
- article
- Published
- 2006-10-01
- Cited by
- 31
- References
- 31
- OpenAlex
- https://openalex.org/W16953214
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:30136488
Keywords
Gibbsite, Aluminosilicate, Lime, Materials science, Cristobalite
References
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- Association between deficiency of mannose-binding lectin and severe infections after chemotherapy.
Cited by
- Structural and functional studies of mannose binding lectin (MBL) and the lectin pathway of complement in children with cancer.
- Genetic variations in multiple myeloma II: association with effect of treatment
- Immunodeficiency and immunotherapy in multiple myeloma
- New directions in the genomics of allogeneic hematopoietic stem cell transplantation.
- Sepsis in acute myeloid leukaemia patients receiving high‐dose chemotherapy: No impact of chitotriosidase and mannose‐binding lectin polymorphisms
- Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation.
- Mannose-binding Lectin Genotype Influences Frequency and Duration of Infectious Complications in Children With Malignancy
- Genetic variants and the risk for invasive mould disease in immunocompromised hematology patients
- Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins.
- Mannan-binding lectin deficiency - Good news, bad news, doesn't matter?
- Mannan-binding lectin in malignancy.
- Antimicrobial therapy of febrile complications after high-dose chemotherapy and autologous hematopoietic stem cell transplantation—guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO)
- Influence of MBL-2 mutations in the infection risk of patients with follicular lymphoma treated with rituximab, fludarabine, and cyclophosphamide
- Influence of mannose-binding lectin genotypes and serostatus in allo-SCT: analysis of 131 recipients and donors
- Mannose-binding lectin polymorphisms and the risk of sepsis: evidence from a meta-analysis
- Infectious complications after chemotherapy and stem cell transplantation in multiple myeloma: Implications of Fc gamma receptor and myeloperoxidase promoter polymorphisms
- Mannose-binding lectin gene variants and infections in patients receiving autologous stem cell transplantation
- Risk stratification and immunogenetic risk for infections following stem cell transplantation
- Low circulating mannan-binding lectin levels correlate with increased frequency and severity of febrile episodes in myeloma patients who undergo ASCT and do not receive antibiotic prophylaxis
- The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT)
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