Drugging tRNA aminoacylation

Keywords

Valencia, Humanities, Art, Biology

References

• Active site titration and aminoacyl adenylate binding stoichiometry of aminoacyl-tRNA synthetases.岡本 務, J S Ashford, C J Bruton — 1975
• Identity determinants of human tRNA(Ser): sequence elements necessary for serylation and maturation of a tRNA with a long extra arm.Tilmann Achsel, H. Groß — 1993
• The exchange of the discriminator base A73 for G is alone sufficient to convert human tRNA(Leu) into a serine‐acceptor in vitro.Kristin Breitschopf, H. Groß — 1994
• Kinetic techniques for the investigation of amino acid: tRNA ligases (aminoacyl-tRNA synthetases, amino acid activating enzymes).Elizabeth Ann Eigner, Robert B. Loftfield — 1974
• Evolution of the tRNA(Tyr)/TyrRS aminoacylation systems.L. Bonnefond, Richard Giegé, Joëlle Rudinger‐Thirion — 2005
• Aminoglycoside binding displaces a divalent metal ion in a tRNA–neomycin B complexNils Mikkelsen, Kenth Johansson, Anders Virtanen — 2001
• Novel classes of antibiotics or more of the same?Anthony Coates, Gerry Halls, Yanmin Hu — 2011
• Aminoacyl tRNA synthetases as targets for new anti‐infectivesPaul Schimmel, Jianshi Tao, Jason M. Hill — 1998
• Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation.Kiyotaka Shiba, Paul Schimmel, Hiromi Motegi — 1994
• The apicoplast: a plastid in Plasmodium falciparum and other Apicomplexan parasites.Bernardo J. Foth, Geoffrey I. McFadden — 2003
• An example of non-conservation of oligomeric structure in prokaryotic aminoacyl-tRNA synthetases. Biochemical and structural properties of glycyl-tRNA synthetase from Thermus thermophilus.Marie‐Hélène Mazauric, Joseph Reinbolt, Bernard Lorber — 1996
• tRNA acceptor stem and anticodon bases form independent codes related to protein foldingCharles W. Carter, Richard Wolfenden — 2015
• Purpuromycin: an antibiotic inhibiting tRNA aminoacylation.S.V. Kirillov, Luca A. Vitali, Beth P. Goldstein — 1997
• The second genetic codeChristian de Duve — 1988
• The identity of the discriminator base has an impact on CCA additionSandra Wende, Serena Bonin, Otto Götze — 2015
• The mechanism of aminoacylation of transfer RNA.Robert B. Loftfield — 1972
• Protein Synthesis Using A Reconstituted Cell-Free SystemCorinna Tuckey, Haruichi Asahara, Ying Zhou — 2014
• Structure of human tryptophanyl-tRNA synthetase in complex with tRNATrp reveals the molecular basis of tRNA recognition and specificityNing Shen — 2006
• Toward a more complete view of tRNA biologyRichard Giegé — 2008
• Structural dynamics of the aminoacylation and proof-reading functional cycle of bacterial leucyl-tRNA synthetaseAndrés Palencia, Thibaut Crépin, Michael Vu — 2012

Cited by

• 11th IUBMB Focused Meeting on the Aminoacyl-tRNA Synthetases: Sailing a New Sea of Complex Functions in Human Biology and DiseaseChristopher S. Francklyn, Hervé Roy, Rebecca W. Alexander — 2018
• Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseasesEun Young Lee, Sung‐Hoon Kim, Myung Hee Kim — 2018
• Transfer RNA function and evolutionPatrick O’Donoghue, Jiqiang Ling, Dieter Söll — 2018
• Lysine Acetylation Regulates Alanyl-tRNA Synthetase Activity in Escherichia coliTakuya Umehara, Saori Kosono, Dieter Söll — 2018
• Uncovering Deep Phylogenetic Signal in Plastid GenomesTravis J. Lawrence — 2018
• Discovery of Small‐Molecule Antibiotics against a Unique tRNA‐Mediated Regulation of Transcription in Gram‐Positive BacteriaKyla M. Frohlich, Spencer Weintraub, Janeen T. Bell — 2019
• Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetaseRicky Cain, Ramya Salimraj, Avinash S. Punekar — 2019
• Translational control of antibiotic resistanceAnne Witzky, Rodney Tollerson, Michael Ibba — 2019
• Self-immunity guided identification of threonyl-tRNA synthetase as the molecular target of obafluorin, a β-lactone antibioticThomas Allan Scott, Sibyl F. D. Batey, Patrick Wiencek — 2019
• Targeting tRNA-synthetase interactions towards novel therapeutic discovery against eukaryotic pathogensPaul Kelly, Fatemeh Hadi-Nezhad, Dennis Liu — 2019
• Dual-targeted hit identification using pharmacophore screeningGalyna P. Volynets, Sergiy A. Starosyla, Mariia Yu. Rybak — 2019
• Molecular evidence for the evolution of the eukaryotic mitochondrial arginyl‐tRNA synthetase from the prokaryotic suborder CystobacterineaeGabor L. Igloi — 2019
• Dual-target inhibitors of mycobacterial aminoacyl-tRNA synthetases among N-benzylidene-N'-thiazol-2-yl-hydrazines.O. P. Kovalenko, Galyna P. Volynets, Mariia Yu. Rybak — 2019
• Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.Junsong Guo, Bingyi Chen, Ying Yu — 2019
• Mutations in ArgS Arginine-tRNA Synthetase Confer Additional Antibiotic Tolerance Protection to Extended-Spectrum-β-Lactamase-Producing Burkholderia thailandensisHyojeong Yi, Jongwook Park, Kwang-Hwi Cho — 2020
• Aminoacyl-tRNA synthetasesMiguel A. Rubio, Michael Ibba — 2020
• Molecular investigation of pathogenic bacteria in the presence of phenolic acidsÖzgün Öykü Özdemir — 2019
• The structural basis of the genetic code: amino acid recognition by aminoacyl-tRNA synthetasesFlorian Kaiser, Sarah Krautwurst, Sebastian Salentin — 2019
• Pseudomonas aeruginosa Presents Multiple Vital Changes in Its Proteome in the Presence of 3-Hydroxyphenylacetic Acid, a Promising Antimicrobial AgentÖzgün Öykü Özdemir, Ferda Soyer — 2020
• A Label-Free Cellular Proteomics Approach to Decipher the Antifungal Action of DiMIQ, a Potent Indolo[2,3-b]Quinoline Agent, against Candida albicans BiofilmsRobert Żarnowski, Anna Jaromin, Agnieszka Zagórska — 2020

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