Fluorescence and autoradiographic evaluation of tau PET ligand PBB3 to α-synuclein pathology
Explore this paper's citation graph
Summary
To clarify whether [11C]PBB3 binds to α‐synuclein pathology, reactivity of PBB3 was assessed by in vitro fluorescence and autoradiographic labeling of brain sections from α‐ synucleinopathies patients.
- Type
- article
- Published
- 2017-04-25
- Cited by
- 72
- References
- 58
- OpenAlex
- https://openalex.org/W28440890
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4494641
Keywords
Political science
References
- Diffuse type of Lewy body disease: progressive dementia with abundant cortical Lewy bodies and senile changes of varying degree--a new disease?
- Diversity of pathological features other than Lewy bodies in familial Parkinson's disease due to SNCA mutations.
- Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.
- Radiation physics for nuclear medicine
- Neuropathology of non-Alzheimer degenerative disorders.
- When DLB, PD, and PSP masquerade as MSA
- [18F]THK-5117 PET for assessing neurofibrillary pathology in Alzheimer’s disease
- Phases of Aβ-deposition in the human brain and its relevance for the development of AD
- Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
- Lewy bodies are located preferentially in limbic areas in diffuse Lewy body disease.
- [18F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease
- In vivo visualization of alpha-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol-5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy.
- Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.
- Theory and Practice of Histological Techniques
- Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.
- Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid.
- Longitudinal Assessment of Aβ and Cognition in Aging and Alzheimer Disease
- Neuropathological stageing of Alzheimer-related changes
- Widespread alterations of alpha-synuclein in multiple system atrophy.
- Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer’s disease patients
Cited by
- In vivo binding of a tau imaging probe, [11C]PBB3, in patients with progressive supranuclear palsy
- PBB3 imaging in Parkinsonian disorders: Evidence for binding to tau and other proteins
- What Would Dr. James Parkinson Think Today? Tau and Other Imaging Possibilities in Parkinson's Disease
- Recent advances in neuropathology, biomarkers and therapeutic approach of multiple system atrophy
- Potential clinical utility of multiple system atrophy biomarkers
- Molecular imaging of tau in the pathological cascade of Alzheimer’s disease
- Tau Imaging in Parkinsonism: What Have We Learned So Far?
- Tau positron emission tomography imaging in tauopathies: The added hurdle of off-target binding
- Amyloid-Beta Radiotracer [18F]BF-227 Does Not Bind to Cytoplasmic Glial Inclusions of Postmortem Multiple System Atrophy Brain Tissue
- Multiple system atrophy and apolipoprotein E
- Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation
- Distinct [18F]THK5351 binding patterns in primary progressive aphasia variants
- In vivo quantification of neurofibrillary tangles with [18F]MK-6240
- Clinical and Imaging Features of Multiple System Atrophy: Challenges for an Early and Clinically Definitive Diagnosis
- Imaging Protein Misfolding in the Brain Using β-Sheet Ligands
- Sex and age interact to determine clinicopathologic differences in Alzheimer’s disease
- PET Molecular Imaging in Familial Parkinson's Disease.
- A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein
- Tau imaging detects distinctive distribution of tau pathology in ALS/PDC on the Kii Peninsula
- Tau PET imaging in neurodegenerative tauopathies—still a challenge
Related papers
No related papers recorded.