Oligomerization process of Bcl-2 associated X protein revealed from intermediate structures in solution.

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Summary

The results not only reveal the on-pathway intermediates, but also suggest a ditopic oligomerization mechanism that may bridge the observed intermediate structures in solution to the large BAX assemblies lately observed on mitochondria.

Type
article
Published
2017-03-15
Cited by
8
References
51

Keywords

Process (computing), Chemistry, Crystallography, Biophysics, Computer science

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