An in vivo gain-of-function screen identifies the Williams-Beuren Syndrome gene GTF2IRD1 as a mammary tumor promoter
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Summary
In vivo screened in vivo ~1,000 genes, that are associated with signaling for positive roles in breast cancer, using lentiviral expression vectors in primary MMTV-ErbB2 mammary tissue, finding one tumor promoting gene, the transcription factor GTF2IRD1.
- Type
- article
- Published
- 2016-05-26
- Cited by
- 17
- References
- 42
- Access
- Open access
- OpenAlex
- https://openalex.org/W27239038
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39180468
Keywords
Computer science
References
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- Determination and Functional Analysis of the Consensus Binding Site for TFII-I Family Member BEN, Implicated in Williams-Beuren Syndrome*
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Cited by
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- Correlation between tripartite motif-containing protein 44 protein expression and the prognosis of postoperative patients exhibiting skin squamous cell carcinoma
- Characteristics of interaction of miRNA with mRNA of breast cancer candidate genes
- CD26/DPP4 - a potential biomarker and target for cancer therapy.
- Low tumour PPM1H indicates poor prognosis in colorectal cancer via activation of cancer-associated fibroblasts
- OMICfpp: a fuzzy approach for paired RNA-Seq counts
- GTF2IRD1 on chromosome 7 is a novel oncogene regulating the tumor‐suppressor gene TGFβR2 in colorectal cancer
- GTF2IRD1 overexpression promotes tumor progression and correlates with less CD8+ T cells infiltration in pancreatic cancer
- Integrated Analysis of the Roles of RNA Binding Proteins and Their Prognostic Value in Clear Cell Renal Cell Carcinoma
- Identification of GTF2IRD1 as a novel transcription factor essential for acute myeloid leukemia
- EpICC: A Bayesian neural network model with uncertainty correction for a more accurate classification of cancer
- New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors
- Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer.
- 5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux
- Enhancement of circular RNA 0002577 in serum exosomes in patients with endometrial cancer accelerates disease progression via general transcription factor II-I repeat domain-containing 1 (GTF2IRD1)
- Lars2-signaling mediates platinum resistance by accumulating cancer stem cell population and suppressing anti-tumor immunity.
- Dietary restriction genes as modulators of breast cancer risk through metabolic pathways
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