A lateral signalling pathway coordinates shape volatility during cell migration
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Summary
A novel pathway, comprised of the planar cell polarity protein Pk1 and the RhoGAPs, Arhgap21/23, that regulates fluctuations in cell shape during productive cell migration is identified.
- Type
- dissertation
- Published
- 2016-05-26
- Cited by
- 53
- References
- 39
- Access
- Open access
- OpenAlex
- https://openalex.org/W27226243
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1839708
Keywords
Humanities, Art
References
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Cited by
- Regulation of Rho GTPases from the lateral sides of migrating cells
- ARHGAP21 as a master regulator of multiple cellular processes
- Planar cell polarity in moving cells: think globally, act locally
- Wnt/Planar Cell Polarity Signaling: New Opportunities for Cancer Treatment.
- A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts.
- Cellular and Molecular Mechanisms Underlying Planar Cell Polarity Pathway Contributions to Cancer Malignancy
- From instruction to output: Wnt/PCP signaling in development and cancer
- The Strength of Mechanical Forces Determines the Differentiation of Alveolar Epithelial Cells.
- Switching between individual and collective motility in B lymphocytes is controlled by cell-matrix adhesion and inter-cellular interactions
- Mapping Cellular Polarity Networks Using Mass Spectrometry-based Strategies.
- The trimeric coiled‐coil HSBP1 protein promotes WASH complex assembly at centrosomes
- ARHGAP21 (Rho GTPase activating protein 21)
- Differential expression and homotypic enrichment of a classic Cadherin directs tissue-level contractile asymmetry during neural tube closure
- ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer
- Wnt/PCP signaling contribution to carcinoma collective cell migration and metastasis
- Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility
- Differential expression and homotypic enrichment of a classic Cadherin directs tissue-level contractile asymmetry during neural tube closure.
- miR-337-3p inhibits gastric tumor metastasis by targeting ARHGAP10
- The functions and regulations of Smurfs in cancers.
- The physiological role of Wnt pathway in normal development and cancer
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