TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer’s disease hippocampus

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Summary

DNA methylation, and particularly 5hmC, may be involved in regulating TREM2 mRNA expression in the AD brain and further studies are guaranteed to investigate in depth the role of 5hmC in AD and other neurodegenerative disorders.

Type
article
Published
2016-04-05
Cited by
85
References
54
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Open access

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