Functional Genomics Uncover the Biology behind the Responsiveness of Head and Neck Squamous Cell Cancer Patients to Cetuximab
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Summary
The biology behind response to platinum-based chemotherapy plus cetuximab in RM-HNSCC cancer is uncovered and may have translational implications improving treatment selection.
- Type
- article
- Published
- 2016-02-26
- Cited by
- 76
- References
- 39
- OpenAlex
- https://openalex.org/W26920888
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13323848
Keywords
Bending, Structural engineering, Forensic engineering, Engineering
References
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- pRRophetic: An R Package for Prediction of Clinical Chemotherapeutic Response from Tumor Gene Expression Levels
- Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes
- Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes
Cited by
- Heads Up! Predictive Gene Signatures in Head and Neck Cancer May Be Coming Soon
- Integrative miRNA-Gene Expression Analysis Enables Refinement of Associated Biology and Prediction of Response to Cetuximab in Head and Neck Squamous Cell Cancer
- Gene Expression Signatures for Head and Neck Cancer Patient Stratification: Are Results Ready for Clinical Application?
- Untangling The Gene-Epigenome Networks: Timing Of Epigenetic Regulation Of Gene Expression In Acquired Cetuximab Resistance
- Basal subtype is predictive for response to cetuximab treatment in patient‐derived xenografts of squamous cell head and neck cancer
- Multicenter Phase II Study of Panitumumab in Platinum Pretreated, Advanced Head and Neck Squamous Cell Cancer
- Are Fusion Transcripts in Relapsed/Metastatic Head and Neck Cancer Patients Predictive of Response to Anti-EGFR Therapies?
- Identification of Novel Signal Transduction, Immune Function, and Oxidative Stress Genes and Pathways by Topiramate for Treatment of Methamphetamine Dependence Based on Secondary Outcomes
- Predicting Radioresistance in Head and Neck Cancer
- Activity and safety of afatinib in a window preoperative EORTC study in patients with squamous cell carcinoma of the head and neck (SCCHN)
- Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas
- Overexpression of PIK3CA in head and neck squamous cell carcinoma is associated with poor outcome and activation of the YAP pathway.
- Do We Still Need Phase 2 Trials? Late Obituary for Panitumumab and the SPECTRUM-Trial
- Genomics Reloaded: Rise of the Expression Profiles
- BET inhibition overcomes receptor tyrosine kinase-mediated cetuximab resistance in HNSCC
- Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial
- Gene signatures and expression of miRNAs associated with efficacy of panitumumab in a head and neck cancer phase II trial.
- DDX3 Activates CBC-eIF3-Mediated Translation of uORF-Containing Oncogenic mRNAs to Promote Metastasis in HNSCC.
- An impaired hepatic clock system effects lipid metabolism in rats with nephropathy
- Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancer
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