Antigen receptors of T helper cells.
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Summary
Since each receptor molecule carries associated with its specific antigen-binding site specific antigenic determinants (so-called idiotopes) that distinguish it from, and can be recognized by, other receptor molecules, it appears possible that the immune system regulates itself by internal receptor-receptor interactions.
- Type
- review
- Published
- 1977-01-01
- Cited by
- 174
- References
- 109
- OpenAlex
- https://openalex.org/W26895232
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25702077
Keywords
Idiotopes, Receptor, Antigen, Immune system, Biology
References
- Immunochemical studies on a mouse myeloma protein with specificity for certain β-linked terminal residues of N-acetyl-d-glucosamine☆
- Antibodies to receptors recognizing histocompatibility antigens.
- Thiamin balance in the sheep.
- Membrane receptors of lymphocytes: By Seiligmannet al. North-Holland, Amsterdam, 1975. 465 pp. $39.75
- Surface immunoglobulins of B and T lymphocytes: molecular properties, association with the cell membrane, and a unified model of antigen recognition.
- THE ROLE OF PRODUCTS OF THE HISTOCOMPATIBILITY GENE COMPLEX IN IMMUNE RESPONSES
- The search for antibodies with molecular uniformity.
- Mouse antibodies to group A streptococcal carbohydrate; use of idiotypy to detect inbred strain specificity and to monitor spleen cell transfer in syngenetic mice.
- Immunochemical and chemical studies on streptococcal group-specific carbohydrates.
- Properties of antigen-specific suppressive T cell factor in the regulation of antibody response of the mouse. II. In vitro activity and evidence for the I region gene product.
- Antigen binding T and B lymphocytes. I. Differences in cellular specificity and influence of metabolic activity on interaction of antigen with T and B cells.
- Inactivation of poly-DL-alanyl bacteriophage T4 with antisera specific toward poly-DL-alanine.
- Comparison of cross-reactivities between albumins of various species at the level of antibody and helper T cells--studies in mice.
- Anti-idiotypic antibody in rat transplantation immunity. I. Production of anti-idiotypic antibody in animals repeatedly immunized with alloantigens.
- Mouse strain-specific idiotypy and interstrain idiotypic cross-reactions.
- Genetics of immunoglobulins in the mouse.
- The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.
- Hypervariable regions, idiotypy, and the antibody-combining site.
- Allotypically related sequences in the Fd fragment of rabbit immunoglobulin heavy chains.
- Antigen binding T and B lymphocytes. II. Studies on the inhibition of antigen binding to T and B cells by anti-immunoglobulin and anti-H-2 sera.
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- Cellular regulation of immune function.
- Neoplasms of immunoregulatory T cells in clinical investigation.
- The T-cell Receptor as Immunoglobulin: Paradigm Regained
- MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.
- On network theory and H-2 restriction.
- Introduction -- the immunoglobulin-like T cell receptor problem.
- Impairment of antigen-specific T cell proliferative response in B cell suppressed mice.
- Recent advances in human cellular immunobiology.
- Membrane immunoglobulins of vertebrate lymphocytes.
- Ontogeny of spontaneous rosette forming cells in mice.
- Molecular interactions and recognition specificity of surface receptors.
- Nonpermeant covalent labels in analytical studies of lymphocyte membrane proteins.
- Hypothesis on the origin of the strong alloreactivity.
- Influence of the major histocompatibility complex on T-cell activation.
- Restriction in IgM expression--I. The VH regions of equine anti-lactose antibodies.
- Ultraviolet-induced suppressor T cells and factor(s) in murine contact photosensitivity. II. Igh-V restriction of T-cell-suppressor factor.
- Idiotypic analysis of anti-I-Ak monoclonal antibodies. III. T- and B-cell responses to anti-Ia idiotopes are not modulated by syngeneic anti-idiotypic monoclonal antibodies.
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