Cytotoxicity of the Sesquiterpene Lactones Neoambrosin and Damsin from Ambrosia maritima Against Multidrug-Resistant Cancer Cells
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Summary
Two known cytotoxic pseudoguaianolide sesquiterpene lactones; neoambrosin and damsin that circumvent MDR may be promising candidates to treat refractory tumors.
- Type
- dissertation
- Published
- 2015-11-09
- Cited by
- 38
- References
- 92
- Access
- Open access
- OpenAlex
- https://openalex.org/W26617519
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13354294
Keywords
Humanities, Art
References
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Cited by
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- Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine
- Oridonin Targets Multiple Drug-Resistant Tumor Cells as Determined by in Silico and in Vitro Analyses
- Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From Centaurea ragusina L.
- An Approach to the 9-Oxo-10-oxabicyclo[5.3.0]dec-2-ene Core of the Guaianolide and Pseudoguaianolide Sesquiterpenes via a Domino Electrocyclic Ring-Opening/Carboxylic Acid Trapping of a gem-Dibromocyclopropane.
- Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation
- Collateral sensitivity of natural products in drug-resistant cancer cells.
- Macrochaetosides A and B, new rare sesquiterpene glycosides from Echinops macrochaetus and their cytotoxic activity
- Pseudoguaianolides: Recent Advances in Synthesis and Applications
- Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines
- Inhibitive behavior of Ambrosia Maritima extract as an eco-friendly corrosion inhibitor for carbon steel in 1M HCI
- Ambrosin, a potent NF-κβ inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin
- Inhibition of HIF-1α through Suppression of NF-κB Activation by Compounds Isolated from Senecio graveolens
- Natural Sesquiterpene Lactones in the Prevention and Treatment of Inflammatory Disorders and cancer: A Systematic Study of this Emerging Therapeutic Approach based on Chemical and Pharmacological Aspect
- Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades
- Ethanolic extract of Artemisia campestris subsp. glutinosa (Besser) Batt. inhibits HIV–1 replication in vitro through the activity of terpenes and flavonoids on viral entry and NF–κB pathway
- Sesquiterpene lactones; Damsin and Neoambrosin suppress cytokine-mediated inflammation in complete Freund's adjuvant rat model via shutting Akt/ERK1/2/STAT3 signaling.
- Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines.
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