Intra-host viral variability in children clinically infected with H1N1 (2009) pandemic influenza.
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Summary
This approach revealed unexpected patterns of co-infection in a 3-week old toddler, arising from rapid and complex reassortment phenomena on a local epidemiological scale, and suggested the possible existence of very low frequency mutants resistant to neuraminidase inhibitors in two untreated patients.
- Type
- article
- Published
- 2015-07-01
- Cited by
- 8
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W25891282
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42925179
Keywords
Adjuvant, Antigen, Immunology, T cell, T helper cell
References
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Cited by
- Genome plasticity of triple-reassortant H1N1 influenza A virus during infection of vaccinated pigs.
- In-Depth Analysis of HA and NS1 Genes in A(H1N1)pdm09 Infected Patients
- Understanding the complex evolution of rapidly mutating viruses with deep sequencing: Beyond the analysis of viral diversity.
- Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms
- Multiple Genome Constellations of Similar and Distinct Influenza A Viruses Co-Circulate in Pigs During Epidemic Events
- Application of deep sequencing methods for inferring viral population diversity.
- Influenza A Virus Subpopulations and Their Implication in Pathogenesis and Vaccine Development.
- High-throughput sequencing (HTS) for the analysis of viral populations.
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