HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4+ T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis
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Summary
It is revealed that productive HIV-1 entry occurs predominantly at the plasma membrane in SupT1-R5, CEM-ss, and primary CD4+ T cells, with little, if any, contribution coming from endocytosed virions.
- Type
- article
- Published
- 2014-09-24
- Cited by
- 64
- References
- 78
- OpenAlex
- https://openalex.org/W25253335
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:206804636
Keywords
Computer science
References
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- IFITM-2 and IFITM-3 but Not IFITM-1 Restrict Rift Valley Fever Virus
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- Endocytosis of HIV: anything goes.
Cited by
- Exploring the Impact of Antiretroviral Drugs on the Cell-to-Cell spread of HIV-1
- Kinetically coupled folding of a single HIV-1 glycoprotein 41 complex in viral membrane fusion and inhibition
- Antigenic Properties of the Human Immunodeficiency Virus Envelope Glycoprotein Gp120 on Virions Bound to Target Cells
- Distinct Requirements for HIV-Cell Fusion and HIV-mediated Cell-Cell Fusion*
- HIV-1 cell-to-cell transmission and broadly neutralizing antibodies
- Reply to “Can HIV-1 Entry Sites Be Deduced by Comparing Bulk Endocytosis to Functional Readouts for Viral Fusion?”
- HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy
- HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus
- Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor
- Folding and Endocytosis of Anthrax Toxin Receptors
- The Early Bird Catches the Worm--Can Evolution Teach us Lessons in Fighting HIV?
- Labeling of virus components for advanced, quantitative imaging analyses
- Super‐resolved insights into human immunodeficiency virus biology
- Cell-to-Cell Spread of HIV and Viral Pathogenesis
- The β-Lactamase Assay: Harnessing a FRET Biosensor to Analyse Viral Fusion Mechanisms
- Cellular Pathways for Productive HIV-1 Entry and Molecular Mechanisms of its Inhibition.
- Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity
- Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction
- Visualization of HIV T Cell Virological Synapses and Virus-Containing Compartments by Three-Dimensional Correlative Light and Electron Microscopy
- Dynamin-2 Stabilizes the HIV-1 Fusion Pore with a Low Oligomeric State
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