Complementary sequence-mediated exon circularization.
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Summary
It is demonstrated that exon circularization is dependent on flanking intronic complementary sequences in human introns and that alternative formation of inverted repeated Alu pairs can lead to alternative circularization, resulting in multiple circular RNA transcripts produced from a single gene.
- Type
- article
- Published
- 2014-09-25
- Cited by
- 1,766
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W25242744
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18390400
Keywords
Computer science
References
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- Expansion of the eukaryotic proteome by alternative splicing
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Cited by
- Competition of RNA splicing: line in or circle up
- Circular RNAs in Brain and Other Tissues: A Functional Enigma.
- CircRNA-protein complexes: IMP3 protein component defines subfamily of circRNPs
- Regulatory role of circular RNAs and neurological disorders
- Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot
- Circular RNA and mRNA profiling reveal competing endogenous RNA networks during avian leukosis virus, subgroup J-induced tumorigenesis in chickens
- High-throughput sequencing reveals circular RNA hsa_circ_0000592 as a novel player in the carcinogenesis of gastric carcinoma
- The mmu_circRNA_37492/hsa_circ_0012138 function as potential ceRNA to attenuate obstructive renal fibrosis
- Long noncoding RNAs: Re-writing dogmas of RNA processing and stability
- RNA editing of non-coding RNA and its role in gene regulation.
- The dynamic epitranscriptome: A to I editing modulates genetic information
- The role of Alu elements in the cis-regulation of RNA processing
- The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells
- The long noncoding RNA regulation at the MYC locus.
- Biogenesis, identification, and function of exonic circular RNAs
- Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development
- Identification and Characterization of Circular RNAs As a New Class of Putative Biomarkers in Human Blood
- Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins
- Splicing noncoding RNAs from the inside out
- Regulatory RNAs discovered in unexpected places
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