A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis
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Summary
An algorithm is developed that relates CERAD scores to TAP scores with high agreement and was found to be a better predictor of dementia than CerAD scores, which indicated that further research is needed to define strategies to relate CERad and TAP Aβ plaque scores to compare their utility and for determining the clinical associations of these different amyloid staging systems with aging and AD.
- Type
- article
- Published
- 2014-06-12
- Cited by
- 29
- References
- 21
- OpenAlex
- https://openalex.org/W24916271
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12606207
Keywords
Computer science
References
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Cited by
- The prevalence of Amyloid pathology in non-demented adults: A meta-analysis and participant-level data analysis.
- Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease
- An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect
- Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy
- Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum
- Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline
- TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss
- Investigating the contribution of astrocytes and neuroinflammation to pathological tau changes in Alzheimer's disease
- Non-Alzheimer’s contributions to dementia and cognitive resilience in The 90+ Study
- Distinctive temporal profiles of detergent-soluble and -insoluble tau and Aβ species in human Alzheimer's disease.
- The “rights” of precision drug development for Alzheimer’s disease
- Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches
- Association of Hypercholesterolemia with Alzheimer’s Disease Pathology and Cerebral Amyloid Angiopathy
- High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer's and Non-Alzheimer's Disease Tauopathies.
- Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia
- Extracellular Sortilin Proteopathy Relative to β-Amyloid and Tau in Aged and Alzheimer’s Disease Human Brains
- Cerebrovascular and Neurodegenerative Pathologies in Long-Term Stable Mild Cognitive Impairment
- Immunogenomics Parameters for Patient Stratification in Alzheimer’s Disease
- Olfactory Bulb Amyloid-β Correlates With Brain Thal Amyloid Phase and Severity of Cognitive Impairment.
- APOE-ε4 and BIN1 increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathology
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