Exercise for depression: efficacy, safety and clinical trial implications.
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Summary
The case of a 48 year-old woman who developed significant elevations in creatine kinase and liver enzyme levels after three work-out sessions consisting of cardiovascular training on an elliptical machine and weightlifting is presented.
- Type
- article
- Published
- 2025-08-12
- Cited by
- 9
- References
- 22
- Access
- Open access
- OpenAlex
- https://openalex.org/W24405729
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40813079
Keywords
Medicine, Clinical trial, Placebo, Depression (economics), Adverse effect
References
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- TREAD: TReatment with Exercise Augmentation for Depression: study rationale and design
- Exercise Testing and Prescription
- Muscular exercise can cause highly pathological liver function tests in healthy men.
- Association between physical activity and mental disorders among adults in the United States.
- Exercise and well-being: a review of mental and physical health benefits associated with physical activity
- Exercise as an Augmentation Strategy for Treatment of Major Depression
- Beneficial effects of exercise and its molecular mechanisms on depression in rats.
- The Spectrum of Rhabdomyolysis
- Effect of Physical Exercise on Some Enzymes in the Serum
- Serum creatine kinase levels and renal function measures in exertional muscle damage.
- The effectiveness of exercise as an intervention in the management of depression: systematic review and meta-regression analysis of randomised controlled trials
- Physical activity reduces the risk of subsequent depression for older adults.
- Exercise for the Treatment of Depression
- [The treatment of major depression].
- Effects of exercise training on older patients with major depression.
- ACSM's Guidelines for Exercise Testing and Prescription
- Physical Activity Counseling and Exercise Prescription
Cited by
- Combined exercise and cognitive behavioral therapy improves outcomes in patients with heart failure
- Current perspectives of the roles of the central norepinephrine system in anxiety and depression
- Survey of Investigators’ Opinions on the Acceptability of Interactions With Patients Participating in Clinical Trials
- Load and the spine. How does the Goldilocks principle apply?
- Barriers to Prescribing Exercise in Clinical Practice to Treat Mild-to-Moderate Depression
- Assessing the Effectiveness of Relaxation Techniques in Management of Anxiety and Depression
- Depression and Pulmonary Arterial Hypertension: Should We be Screening for Depressive Symptoms?
- Depression: Beyond Description As an Important Comorbidity in Pulmonary Arterial Hypertension—The Next Steps
- Effects of exercise on depression and anxiety in patients with chronic pain: A systematic review and meta-analysis of randomized controlled trials.
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